Results 121 to 130 of about 420 (241)

On the Molecular Diffusion Dynamics Between Subcutaneous Tissue and Microneedles for Wearable Continuous Glucose Monitoring

open access: yesAdvanced NanoBiomed Research, EarlyView.
In this study, we investigate the dynamics of glucose diffusion between subcutaneous tissue and hydrogel‐filled microneedles. Specifically, we examine how hydrogel thickness, microneedle size, and glucose concentration influence diffusion. This study provides an experimental reference to the wearable biosensor community researching microneedle‐based ...
Wensheng Lin   +9 more
wiley   +1 more source

Numerical and Experimental Study of Mixing Characteristics in a Spiral Micromixer

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Significant enhancement of mixing performance can be achieved by Dean vortices in spiral channels. In order to deeply explore the mixing mechanisms and variation laws in spiral micromixers, this work designed a spiral micromixer and adopted a combined method of experiments and numerical simulations to analyze the mixing performance and ...
Anming Yang, Shiqing Zheng
wiley   +1 more source

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles

open access: yesBMEMat, EarlyView.
Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu   +9 more
wiley   +1 more source

A novel biomimetic liposome drug delivery system mediated by macrophage targeting for precision treatment of encephalitis

open access: yesBMEMat, EarlyView.
An advanced macrophage‐mediated biomimetic liposome (AC‐LP@RAW) that can penetrate the BBB and precisely target inflammatory sites in the deep brain was established in this study based on the unique immune homing property of macrophages, and showed a significantly improved delivery of curcumin to the brain.
Mengru Wu   +5 more
wiley   +1 more source

Ultrasmall Fe‐curcumin immunomodulators reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence

open access: yesBMEMat, EarlyView.
This work discovered a novel research that ultrasmall Fe‐curcumin immunomodulators could reinvigorate CAR‐T cells to potentiate solid tumor immunotherapy by mitigating cell exhaustion and senescence. Abstract CAR‐T cell immunotherapy has achieved exciting success in hematologic malignancies, but the therapeutic efficacy is relatively limited in solid ...
Jiazhi Duan   +15 more
wiley   +1 more source

Selective Synthesis of N,N‐Dimethylformamide From CO2 Hydrogenation Coupled With Dimethylamine Over a ZnZrOx Solid‐Solution Catalyst

open access: yesCarbon and Hydrogen, EarlyView.
N‐formylation of dimethylamine though CO2 hydrogenation takes place at a ZnZrOx solid‐solution catalyst surface toward N,N‐dimethylformamide. By synergistic effect of Zn and Zr sites, the catalyst achieves 99% DMF selectivity at 14% DMA conversion at 280°C with at least 1000 h stability on steam.
Jinxin He   +10 more
wiley   +1 more source

Protic Ionic Liquid‐Mediated Liquid‐Phase Exfoliation of Titanium Disulfide for Photocatalytic CO2 Reduction Reaction

open access: yesCarbon and Hydrogen, EarlyView.
A green and highly efficient liquid‐phase exfoliation technology is reported to produce TiS2 nanosheets from a corresponding bulk powder in protic ionic liquid‐ γ‐valerolactone solution under ambient conditions, and the exfoliation yield is up to 35.5%.
Chaojie Pang   +5 more
wiley   +1 more source

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