Results 151 to 160 of about 97,519 (271)

Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare

Advanced Robotics Research, EarlyView.
Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin, Jimin Kim, Inho Kim, Bong Hoon Kim   +3 more
wiley   +1 more source

Single-Cell Sequencing Reveals the Immunosuppressive Trajectory in the Tumor Microenvironment of Human Giant Cell Tumor of Bone. [PDF]

Biomed Res Int
Liu Y, Luo W, Xu Y, Yao X, Dai L, Feng Q, Wang P, Yang W, Feng Y, Miao H, Huang S, Ye D.   +11 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Single cell atlas decodes the molecular dynamics of scar repair after human rotator cuff tear. [PDF]

Bone Res
Qin Y, Yang G, Zhang T, Yang Y, Wan L, Zhang T, Wang L, Hu Z, Dai Z, Zhou H, Li C, Hu J, Lu H.   +12 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Large-scale single-cell analysis and in silico perturbation reveal dynamic evolution of HCC: from initiation to therapeutic targeting. [PDF]

NPJ Precis Oncol
Xia P, Shuang S, Fu D, Liu L, Yang D, Guo Y, Tian Y, Ji P, Yuan X, Tian Y, Shen R, Wang D.   +11 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

LDRT combined with anti-PD-1 promotes tumor regression in head and neck squamous cell carcinoma through tumor metaprogram evolution and immune cell reprogramming. [PDF]

J Exp Clin Cancer Res
Li G, Yang X, Huang L, Zheng Y, Xu L, Zhang Z, Li J, Li T, Zhang Y, Yang Y, Li Y, Liu Z.   +11 more
europepmc   +1 more source

Micro-Expression Recognition by Motion Feature Extraction based on Pre-training

Micro-expressions (MEs) are spontaneous, unconscious facial expressions that have promising applications in various fields such as psychotherapy and national security.
Li, Ruolin, Li, Yongchun, Ma, Bingyang, Wang, Lu, Wei, Hongchao, Xu, Lisheng, Yang, Tingting   +6 more
core  

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source