Results 221 to 230 of about 97,519 (271)

Age-stratified analysis of therapeutic, immune, and glycosylation gene expression in colorectal cancer using machine learning. [PDF]

Sci Rep
Celik H, Bansal B, Gill JS, Correa JK, Herman K, Goyal R, Çelik V, Guo K, Mathur R.   +8 more
europepmc   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

A hybrid local-global feature attention network for thin section rock image classification. [PDF]

Sci Rep
Wei P, Fan C, Yang X, Zhang J, Deng X, Gan J, Li Z.   +6 more
europepmc   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source

Improving atlas-scale single-cell annotation models with hierarchical cross-entropy loss. [PDF]

Nat Comput Sci
Cultrera di Montesano S, D'Ascenzo D, Raghavan S, Amini AP, Winter PS, Crawford L.   +5 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Macroscopic modelling and analysis based on microscopic models for swarm systems. [PDF]

Sci Rep
Quan Q, Yu X, Li Y, Qi G.
europepmc   +1 more source

Wrinkle‐Adaptive Kirigami Wearables With Anisotropic Deformability for Sleep EEG Monitoring

Advanced Science, EarlyView.
This article introduces a wrinkle‐adaptive, kirigami‐structured wearable EEG patch that personalizes electrode‐skin conformity to stabilize the interface and enable wireless, high‐quality sleep monitoring. ABSTRACT Wearable electroencephalography (EEG) devices offer a promising solution for continuous brain monitoring outside laboratory settings ...
Jungmin Kim, Ka Ram Kim, Byeongjun Lee, Cheoljeong Park, Seong J. Cho, Woon‐Hong Yeo   +5 more
wiley   +1 more source

Enhanced cell contact and planarian tissue extract increase DNA replication and viability for neoblast cultivation. [PDF]

iScience
Zhang W, Yang L, Li N, Lei K.
europepmc   +1 more source