Results 31 to 40 of about 2,207,642 (292)

Preservice Teachers Respond to And Tango Makes Three: Deconstructing Disciplinary Power and the Heteronormative in Teacher Education [PDF]

open access: yes, 2012
This study employs Foucauldian concepts to analyse macro and micro contexts of publicly spoken and silent discourses describing ‘homosexuality,’ ‘education’ and ‘teacher’ in order to identify teacher subject positions available to preservice teachers ...
Larson, Mindy Legard   +1 more
core   +2 more sources

Macro F1 and Macro F1

open access: yes, 2019
The 'macro F1' metric is frequently used to evaluate binary, multi-class and multi-label classification problems. Yet, we find that there exist two different formulas to calculate this quantity. In this note, we show that only under rare circumstances the two computations can be considered equivalent.
Opitz, Juri, Burst, Sebastian
openaire   +2 more sources

Análise estatística e pluriescalar das desigualdades educacionais: aspirações científicas e desempenho de estudantes no ENEM [PDF]

open access: yesSociologias
Resumo A literatura sociológica reitera a existência de desigualdades educacionais associadas às desigualdades sociais. O desempenho escolar e a aspiração por carreiras científicas revelam distinções educacionais, de classe e de gênero.
Matheus Monteiro Nascimento   +3 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

miR-125b-5p upregulation by TRIM28 induces cisplatin resistance in non-small cell lung cancer through CREB1 inhibition

open access: yesBMC Pulmonary Medicine, 2022
Objective miR-125b-5p plays an important role in the development of cancer and drug resistance. However, in cisplatin resistance of non-small cell lung cancer (NSCLC), the function and potential mechanism of miR-125b-5p is still unclear.
Qiuyu Tan   +8 more
doaj   +1 more source

Decentralized Cooperative Planning for Automated Vehicles with Hierarchical Monte Carlo Tree Search

open access: yes, 2018
Today's automated vehicles lack the ability to cooperate implicitly with others. This work presents a Monte Carlo Tree Search (MCTS) based approach for decentralized cooperative planning using macro-actions for automated vehicles in heterogeneous ...
Kurzer, Karl   +2 more
core   +1 more source

Multiscale computational homogenization: review and proposal of a new enhanced-first-order method [PDF]

open access: yes, 2018
This is a copy of the author 's final draft version of an article published in the Archives of computational methods in engineering. The final publication is available at Springer via http://dx.doi.org/10.1007/s11831-016-9205-0The continuous increase of ...
Martínez García, Javier   +2 more
core   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Longitudinal growth of the Saccharina kelp embryo depends on actin filaments that control the formation of a corset-like structure composed of alginate

open access: yesScientific Reports
The initiation of embryogenesis in the kelp Saccharina latissima is accompanied by significant anisotropy in cell shape. Using monoclonal antibodies, we show that this anisotropy coincides with a spatio-temporal pattern of accumulation of alginates in ...
Samuel Boscq   +6 more
doaj   +1 more source

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