Results 351 to 360 of about 1,540,630 (392)
Granuloma macrophage differentiation [PDF]
Nature Reviews Immunology, 2016 Multinuclear granuloma macrophages arise through a distinct differentiation pathway mediated by chronic TLR2 signalling, rather than by cell fusion.
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BioEssays, 1995
AbstractThe macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied ...
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AbstractThe macrophage plays an important role in host development and physiology, and in pathogenesis of many infectious, immunologic and degenerative disease processes. It displays marked heterogeneity of phenotype in different tissues, reflecting local interactions with other cell types, and contributes to host homeostasis through a varied ...
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Cellular Immunology, 1983
It is a pleasure and a privilege to be here today to honor Lewis Thomas. As I look out on this distinguished audience and see so many good friends, it brings on an attack of nostalgia for the early sixties on the sixth floor of Building D in Bellevue. Those years with Jerry and Lew were some of the most exciting and satisfying of my career. The sixties
Roberta A. David +4 more
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It is a pleasure and a privilege to be here today to honor Lewis Thomas. As I look out on this distinguished audience and see so many good friends, it brings on an attack of nostalgia for the early sixties on the sixth floor of Building D in Bellevue. Those years with Jerry and Lew were some of the most exciting and satisfying of my career. The sixties
Roberta A. David +4 more
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Frontiers in Bioscience, 2008
Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra Nardin, Jean-Pierre Abastado
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Macrophages are ubiquitous cells physiologically involved in a variety of processes including pathogen destruction, inflammation, tissue repair and remodeling. They have a highly plastic phenotype and their functional polarization is determined by cytokines and factors found within local microenvironments.
Alessandra Nardin, Jean-Pierre Abastado
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Reproductive Sciences, 2008
During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil Mor, Kaori Koga
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During implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo. Yet the regulation of apoptosis is also imperative for a successful pregnancy. The quick and effective removal of apoptotic cells by tissue macrophages represents an essential process, which prevents the ...
Gil Mor, Kaori Koga
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Atherosclerosis and Macrophages
Acta Pathologica Japonica, 1989Atherosclerosis is undoubtedly a disease of many facets and in this review we have merely touched one angle of this issue. The best‐established cause of the disease is hyper‐cholesterolemia. Since the important role of macrophages in lipoprotein metabolism has been confirmed, current interest is focused on the role of macrophages in atherosclerosis ...
Jianglin Fan +3 more
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Cancer and Metastasis Reviews, 1990
The uncontrolled growth of metastases resistant to conventional therapeutic modalities is a major cause of death from cancer. Data from our laboratory and others indicate that metastases arise from the nonrandom spread of specialized malignant cells that preexist within a primary neoplasm.
Isaiah J. Fidler +4 more
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The uncontrolled growth of metastases resistant to conventional therapeutic modalities is a major cause of death from cancer. Data from our laboratory and others indicate that metastases arise from the nonrandom spread of specialized malignant cells that preexist within a primary neoplasm.
Isaiah J. Fidler +4 more
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Comparative Immunology, Microbiology and Infectious Diseases, 1985
The role of macrophages is essential in the development of a normal immune response. Not only are these cells involved in the initiation of this response by presenting antigens to lymphocytes and by producing Interleukin I, but they also participate in the various phenomena of cellular co-operation and regulation.
E Schneider, M Dy
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The role of macrophages is essential in the development of a normal immune response. Not only are these cells involved in the initiation of this response by presenting antigens to lymphocytes and by producing Interleukin I, but they also participate in the various phenomena of cellular co-operation and regulation.
E Schneider, M Dy
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2002
Publisher Summary This chapter examines macrophages, which are a family of mononuclear leukocytes that are widely distributed throughout most tissues. They vary considerably in phenotype depending on the local microenvironment, involved in the scavenging of dying cells, pathogens, and molecules through phagocytosis and endocytosis.
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Publisher Summary This chapter examines macrophages, which are a family of mononuclear leukocytes that are widely distributed throughout most tissues. They vary considerably in phenotype depending on the local microenvironment, involved in the scavenging of dying cells, pathogens, and molecules through phagocytosis and endocytosis.
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Macrophages and the glucocorticoids
Journal of Neuroimmunology, 1992Macrophages fulfill such functions as (i) housekeeping and scavenging, (ii) protective and defense, and (iii) memory. Glucocorticoids are hormones also used as anti-inflammatory and immuno-suppressive drugs. They act on the many functions of macrophages, mainly by interfering with functions (ii) and (iii).
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