Results 161 to 170 of about 851,361 (268)

TAM-targeted nanomedicine in cancer: biological basis, therapeutic strategies, and translational perspectives. [PDF]

Theranostics
Zhou L, Yuan F, Wu Y, Li X, Xiang D.
europepmc   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Tumor-derived HMGB2 induces M2-like macrophage polarization via TRIM65-mediated NLRP3 degradation to promote DLBCL progression. [PDF]

J Immunother Cancer
He S, Liu Y, Tang Y, Zhai L, Luo X, Zhao M, Xiao Q, Xie X, Fu H, Li J, Li Y, Shu X, Yang Z, Liu Y, Zhang X.   +14 more
europepmc   +1 more source

Mechanically Compliant, Precision‐Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration

Advanced Healthcare Materials, EarlyView.
This study explores how the brain responds to implants of different properties. Hydrogels with various mechanical properties and pore sizes were implanted in adult rat brains. It is observed that hydrogels with mechanical property closely matched to the brain and 40 µm pore size elicit a pro‐healing response from the brain by modulating the immune ...
Ian Dryg, Le Zhen, Rebecca Darrow, Savannah Lawton, Lars Crawford, Robert Robinson, Steve Perlmutter, James D. Bryers, Buddy D. Ratner   +8 more
wiley   +1 more source

Melanoma stem cells drive macrophage reprogramming to a hybrid phenotype, modulating melanoma stemness and compromising NK cell-mediated immunity. [PDF]

Front Immunol
Anselmi M, Francesconi M, Triulzi T, Bernardo G, Le Noci V, Bianchi F, Castagnoli L, Arnaboldi F, Gagliano N, Pupa SM, Limonta P, Sfondrini L, Sommariva M.   +12 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The Impact of Airway Oxidative Stress on Macrophage Polarization in Stable Asthma and COPD: Association With Clinical Features in a Prospective Observational Study. [PDF]

J Cell Mol Med
Paplińska-Goryca M, Proboszcz M, Wróbel M, Radziszewska M, Mycroft-Rzeszotarska K, Krenke R.   +5 more
europepmc   +1 more source

Macrophage manipulation [PDF]

Nature Reviews Cancer, 2019
openaire   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Dapagliflozin binds PRMT7 to inhibit p38 MAPK phosphorylation and macrophage foam cell formation in atherosclerosis. [PDF]

iScience
Fang Y, Li S, Qin C, Chou Y, Sun N, Ma Y, Zhou Y, Li H, Feng H, Yuan X, Ye H, Wu X, Kang N, Chen H, Gao L, Cao F.   +15 more
europepmc   +1 more source