Results 81 to 90 of about 1,175,217 (343)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Peculiarities of the babesiosis infection influence to nonlinear mice stomach structure (experimental and morphological investigation.

Annals of Mechnikov's Institute, 2020
The babesias are one of the most ubiquitous and widespread blood parasites in the worldbased on numbers and distribution of species in animals, second only to the trypanosomes .
S Pokhil, I Torianik, O Tymchenko, N Chigirinska, I Kostyria, T Boletch'ka   +5 more
doaj  

Structural uterine changes in postpartum endometritis in cows [PDF]

Veterinary World, 2018
Aim: The purpose of this work was to study the dynamics of structural manifestations of acute cases of postpartum endometritis in cows. Materials and Methods: The light and electron microscopy methods were used when studying structural changes in the ...
S. M. Suleymanov, B. V. Usha, Yu. A. Vatnikov, E. D. Sotnikova, Eu. V. Kulikov, V. I. Parshina, M. V. Bolshakova, M. U. Lyshko, E. V. Romanova   +8 more
doaj   +1 more source

New Insights into the Communications of the Facial Vein with the Dural Venous Sinuses

Medicina, 2023
Background and Objectives: Anastomoses of the extracranial and intracranial venous system have been described in the literature. The presence of such anastomoses may facilitate a possible spread of infection into the dural venous sinuses.
Martin Siwetz, Hannes Widni-Pajank, Niels Hammer, Ulrike Pilsl, Simon Bruneder, Andreas Wree, Veronica Antipova   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Digital reconstruction of squeezed light for quantum information processing

npj Quantum Information
Squeezed light plays a vital role in quantum information processing. However, its highly sensitive nature presents significant practical challenges, particularly in remote detection, which traditionally requires complex systems such as active phase ...
Huy Q. Nguyen, Ivan Derkach, Adnan A. E. Hajomer, Hou-Man Chin, Akash nag Oruganti, Ulrik L. Andersen, Vladyslav Usenko, Tobias Gehring   +7 more
doaj   +1 more source

Collective Phase Sensitivity

, 2008
The collective phase response to a macroscopic external perturbation of a population of interacting nonlinear elements exhibiting collective oscillations is formulated for the case of globally-coupled oscillators.
A. T. Winfree, Hiroshi Kori, Hiroya Nakao, Kensuke Arai, S. C. Manrubia, Y. Kuramoto, Yoji Kawamura, Yoshiki Kuramoto   +7 more
core   +1 more source

Dynamical Tunneling in Macroscopic Systems [PDF]

Physical Review Letters, 2007
We investigate macroscopic dynamical quantum tunneling (MDQT) in the driven Duffing oscillator, charateristic for Josephson junction physics and nanomechanics. Under resonant conditions between stable coexisting states of such systems we calculate the tunneling rate.
Serban, I., Wilhelm, F. K.
openaire   +3 more sources

From nanoscopic to macroscopic photo-driven motion in azobenzene-containing materials

Nanophotonics, 2018
The illumination of azobenzene molecules with UV/visible light efficiently converts the molecules between trans and cis isomerization states. Isomerization is accompanied by a large photo-induced molecular motion, which is able to significantly affect ...
S. Oscurato, M. Salvatore, P. Maddalena, A. Ambrosio   +3 more
semanticscholar   +1 more source

Emergence of macroscopic directed motion in populations of motile colloids [PDF]

Nature, 2013
From the formation of animal flocks to the emergence of coordinated motion in bacterial swarms, populations of motile organisms at all scales display coherent collective motion.
A. Bricard, Jean-Baptiste Caussin, N. Desreumaux, O. Dauchot, D. Bartolo   +4 more
semanticscholar   +1 more source