Results 41 to 50 of about 4,786 (269)
Development of zeaxanthin‐rich tomato fruit through genetic manipulations of carotenoid biosynthesis
Plant Biotechnology Journal, Volume 18, Issue 11, Page 2292-2303, November 2020., 2020 Summary The oxygenated carotenoid zeaxanthin provides numerous benefits to human health due to its antioxidant properties. Especially it is linked to protecting, together with the xanthophyll lutein, the retina in the human eye by filtering harmful blue light thus delaying the progression of age‐related macular degeneration (AMD), the most prevalent ...
Uri Karniel +3 more
wiley +1 more source
Anomalous angiogenesis in retina [PDF]
Biomedicines 9, 224 (2021), 2021 Age-related macular degeneration (AMD) may cause severe loss of vision or blindness particularly in elderly people. Exudative AMD is characterized by angiogenesis of blood vessels growing from underneath the macula, crossing the blood-retina barrier (that comprise Bruch's membrane, BM, and the retinal pigmentation epithelium RPE), leaking blood and ...
arxiv +1 more source
Sjögren‐Larsson syndrome: The mild end of the phenotypic spectrum
JIMD Reports, Volume 53, Issue 1, Page 61-70, May 2020., 2020 Abstract Sjögren‐Larsson syndrome (SLS) is a rare inborn error of lipid metabolism. The syndrome is caused by mutations in the ALDH3A2 gene, resulting in a deficiency of fatty aldehyde dehydrogenase. Most patients have a clearly recognizable severe phenotype, with congenital ichthyosis, intellectual disability, and spastic diplegia.
Pippa Staps +8 more
wiley +1 more source
Complement inhibitors for age-related macular degeneration [PDF]
, 2014 Given the relatively high prevalence of age-related macular degeneration (AMD) and the increased incidence of AMD as populations age, the results of trials of novel treatments are awaited with much anticipation.
Chakravarthy, Usha +2 more
core +1 more source
A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery
Journal of Ophthalmology, Volume 2020, Issue 1, 2020., 2020 Retinitis pigmentosa (RP) is a set of inherited retinal degenerative diseases that affect photoreceptor and retinal pigment epithelial cells (RPEs), possibly associated with some ocular complications, including cataract. The complicated cataract formation is most likely the result of RP‐related inflammation response, and the most common morphology ...
Yingying Hong +4 more
wiley +1 more source
Multiscale Softmax Cross Entropy for Fovea Localization on Color Fundus Photography [PDF]
arXiv, 2021 Fovea localization is one of the most popular tasks in ophthalmic medical image analysis, where the coordinates of the center point of the macula lutea, i.e. fovea centralis, should be calculated based on color fundus images. In this work, we treat the localization problem as a classification task, where the coordinates of the x- and y-axis are ...
arxiv
, 1996 Polyenes are important for vision in all sighted species. The visual pigments (the rhodopsins) all use 11-cis-retinal as the chromophore; some possible reasons for the importance of this isomer are now emerging.
Rando, Robert R.
core +1 more source
Valores de Referência da Tomografia de Coerência Óptica na Idade Pediátrica
Acta Médica Portuguesa, 2015 Introdução: A tomografia de coerência óptica é um exame que permite obter imagens de alta resolução dos tecidos in vivo, possibilitando a medição das estruturas oculares, nomeadamente a camada de fibras nervosas da retina e a espessura macular.
Tatiana Queirós +2 more
doaj +1 more source
A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease
Antioxidants, 2020 Carotenoids are natural lipid-soluble antioxidants abundantly found as colorful pigments in fruits and vegetables. At least 600 carotenoids occur naturally, although about 20 of them, including β-carotene, α-carotene, lycopene, lutein, zeaxanthin, meso ...
Fatima Tuj Johra +3 more
doaj +1 more source
Are Macula or Optic Nerve Head Structures better at Diagnosing Glaucoma? An Answer using AI and Wide-Field Optical Coherence Tomography [PDF]
arXiv, 2022 Purpose: (1) To develop a deep learning algorithm to automatically segment structures of the optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) scans; (2) To assess whether 3D macula or ONH structures (or the combination of both) provide the best diagnostic power for glaucoma.
arxiv