Results 121 to 130 of about 160,800 (350)

Prevalence of age related macular degeneration in persons aged 50 years and over resident in Australia. [PDF]

, 1993
R. A. Mitchell
openalex   +1 more source

Macrophages related to Bruch's membrane in age-related macular degeneration [PDF]

, 1990
Murray C. Killingsworth, J P Sarks, S H Sarks   +2 more
openalex   +1 more source

Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations. [PDF]

, 2019
PurposeTo determine whether high-resolution retinal imaging measures of macular structure correlate with visual function over 36 months in retinal degeneration (RD) patients and normal subjects.MethodsTwenty-six eyes of 16 RD patients and 16 eyes of 8 ...
Baldwin, Angela, De la Huerta, Irina, Duncan, Jacque L, Foote, Katharina G, Gustafson, Kevin, Porco, Travis C, Rinella, Nicholas, Roorda, Austin, Zayit-Soudry, Shiri   +8 more
core   +1 more source

Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration

Neural Regeneration Research
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal degenerative diseases.
Xiaoxu Huang, Yumeng Zhang, Yuxin Jiang, Tong Li, Shiqi Yang, Yimin Wang, Bo Yu, Minwen Zhou, Guanran Zhang, Xiaohuan Zhao, Junran Sun, Xiaodong Sun   +11 more
doaj   +1 more source

Transforming Growth Factor‐β‐Activated Protein 1 (TAK1) Regulates Necroptosis in Age‐Related Hearing Loss

Aging Cell, EarlyView.
TAK1‐mediated necroptotic pathways play an important role in the pathogenesis of ARHL. ABSTRACT Inflammation plays an important role in age‐related hearing loss (ARHL). Transforming growth factor‐β‐activated protein 1 (TAK1), a key factor upstream of inflammatory pathways, mediates various cell death pathways, potentially influencing the survival and ...
Hanjing Wang, Yayun Lv, He Zhao, Zhihong Hao, Xiaoyu Zhai, Yan Wang, Jingjing Qiu, Liang Chen, Jiamin Zhou, Limei Cui, Yan Sun   +10 more
wiley   +1 more source

Vitelliform macular degeneration associated with mitochondrial myopathy. [PDF]

, 1992
Girish Modi, Jessica Heckman, D Saffer
openalex   +1 more source

Qualitative assessment of online information about age-related macular degeneration available in Portuguese

Einstein (São Paulo)
Objective: To evaluate the quality of online information on age-related macular degeneration available in Portuguese. Methods: The search term “age-related macular degeneration” was used to browse the web using four different search engines.
Jorge Agi, Niro Kasahara, Claudio Luiz Lottenberg   +2 more
doaj   +1 more source

Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD‐Like Pathology in Mice

Aging Cell, EarlyView.
Our study reveals that overactivation of both mTOR complexes through mLST8 in RPE cells triggers AMD‐like pathology and cellular dysfunction. This finding highlights the critical role of balanced mTOR signaling in retinal health and suggests that targeting both complexes could be therapeutic for AMD treatment.
Olivia Chowdhury, Sridhar Bammidi, Pooja Gautam, Vishnu Suresh Babu, Haitao Liu, Peng Shang, Ying Xin, Emma Mahally, Mihir Nemani, Victoria Koontz, Kira Lathrop, Katarzyna M. Kedziora, Jonathan Franks, Ming Sun, Joshua W. Smith, Lauren R. DeVine, Robert N. Cole, Nadezda Stepicheva, Anastasia Strizhakova, Sreya Chattopadhyay, Stacey Hose, Jacob Samuel Zigler Jr., José‐Alain Sahel, Jiang Qian, Prasun Guha, James T. Handa, Sayan Ghosh, Debasish Sinha   +27 more
wiley   +1 more source

Drusen in age-related macular degeneration [PDF]

, 1994
I H Chisholm
openalex   +1 more source

The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age

Aging Cell, EarlyView.
The effects of the mitochondria‐targeted peptide therapeutic elamipretide on age‐related muscle function were compared with its effects on molecular biomarkers of aging. It was found that elamipretide treatment partially reverses age‐related cardiac dysfunction and skeletal muscle weakness in mice without significantly affecting muscle epigenetic or ...
Wayne Mitchell, Gavin Pharaoh, Alexander Tyshkovskiy, Matthew Campbell, David J. Marcinek, Vadim N. Gladyshev   +5 more
wiley   +1 more source