Results 121 to 130 of about 170,520 (332)
Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration
Neural Regeneration ResearchProgressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal degenerative diseases.
Xiaoxu Huang +11 more
doaj +1 more source
Vitelliform macular degeneration associated with mitochondrial myopathy. [PDF]
, 1992 Girish Modi, Jessica Heckman, D Saffer
openalex +1 more source
Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. [PDF]
, 2017 PurposeMetabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. Previously, we reported on progressive retinal degeneration in a spontaneous obese rat (WNIN/Ob) model.
Ayyagari, Radha +7 more
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Six Drivers of Aging Identified Among Genes Differentially Expressed With Age
Aging Cell, EarlyView.A meta‐analysis of 25 transcriptomic datasets from mammalian tissues revealed 45 genes consistently upregulated or downregulated with age. Orthologs of these genes were functionally evaluated using Caenorhabditis elegans lifespan screens to reveal those with causal roles in the aging process, thus identifying six evolutionarily conserved drivers of ...
Ariella Coler‐Reilly +3 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao +5 more
wiley +1 more source
Einstein (São Paulo)Objective: To evaluate the quality of online information on age-related macular degeneration available in Portuguese. Methods: The search term “age-related macular degeneration” was used to browse the web using four different search engines.
Jorge Agi +2 more
doaj +1 more source
Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans
Acta Ophthalmologica, EarlyView.Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou +8 more
wiley +1 more source
Macular function impairment in eyes with early age-related macular degeneration [PDF]
, 1997 C Degli +4 more
openalex +1 more source
New and emerging technologies for the treatment of inherited retinal diseases: a horizon scanning review. [PDF]
, 2015 The horizon scanning review aimed to identify new and emerging technologies in development that have the potential to slow or stop disease progression and/or reverse sight loss in people with inherited retinal diseases (IRDs).
Michaelides, M +4 more
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