Results 151 to 160 of about 511,582 (401)

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

open access: yesNature Communications, 2019
Age-related macular degeneration (AMD) is the most common cause of blindness among the elderly in the developed world. While treatment is effective for the neovascular or “wet” form of AMD, no therapy is successful for the non-neovascular or “dry” form ...
J. Handa   +8 more
semanticscholar   +1 more source

The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration

open access: yesNeural Regeneration Research
Age-related macular degeneration is a serious neurodegenerative disease of the retina that significantly impacts vision. Unfortunately, the specific pathogenesis remains unclear, and effective early treatment options are consequently lacking.
Qianzi Jin   +4 more
doaj   +1 more source

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration

open access: yesOphthalmology and Therapy
Introduction Neovascular age-related macular degeneration is a global public-health concern, associated with a considerable burden to individuals, healthcare systems, and society.
Anat Loewenstein   +22 more
doaj   +1 more source

Integrated Roles of Systemic Diseases and Serum Biomarkers in the Incidence of Age‐Related Macular Degeneration: The UK Biobank Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu   +9 more
wiley   +1 more source

Recent Advancements in the Treatment of Age‐Related Macular Degeneration

open access: yesMed Research, EarlyView.
ABSTRACT Age‐related macular degeneration (AMD) is a prevalent cause of visual impairment and blindness among the elderly. AMD can be categorized into two subtypes: “wet” and “dry.” Current treatments for wet AMD mainly involve anti‐vascular endothelial growth factor (VEGF) drugs, and there are three U.S.
Shan Liu   +10 more
wiley   +1 more source

Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration

open access: yesNeural Regeneration Research
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal degenerative diseases.
Xiaoxu Huang   +11 more
doaj   +1 more source

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