Results 181 to 190 of about 410,667 (361)

Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle‐associated protein: Implications for diabetic retinopathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Plasmalemma vesicle‐associated protein (PLVAP) regulates transcytosis in vascular endothelial cells. PLVAP expression is increased in pathological conditions, such as diabetic retinopathy. P2X7 receptor antagonists have been shown to preserve blood‐retinal barrier (BRB) integrity.
Chiara Bianca Maria Platania   +16 more
wiley   +1 more source

Utilització de Bevacizumab en patologia diferent de la degeneració macular associada a l'edat [PDF]

open access: yes, 2011
INTRODUCCIÓ L'angiogènesi és el procés que condueix a la formació de nous vasos sanguinis a partir de la vascularització preexistent. Disposem en l'actualitat de diversos fàrmacs que inhibeixen un factor proangiogènic, el factor de creixement de l ...
Cano Parra, Juan   +4 more
core   +1 more source

Safety and effectiveness of fingolimod in Japanese patients with multiple sclerosis: Results of a post‐marketing surveillance study

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective Fingolimod is the first oral sphingosine‐1‐phosphate receptor modulator approved in Japan for multiple sclerosis (MS). A large Japanese observational study of fingolimod in patients with MS was carried out to support its safety and effectiveness in a real‐world setting.
Noriko Sato   +7 more
wiley   +1 more source

Fully Automated Segmentation of Hyperreflective Foci in Optical Coherence Tomography Images [PDF]

open access: yesarXiv, 2018
The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease characteristics. The presence of hyperreflective foci (HRF) is related to disease progression in various retinal diseases ...
arxiv  

Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]

open access: yes, 2011
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H.   +2 more
core  

Impact of cataract surgery on patients receiving intravitreal therapy for retinal vein occlusion

open access: yesClinical &Experimental Ophthalmology, EarlyView.
Abstract Background To assess clinical outcomes of cataract surgery in eyes treated with intravitreal injections for cystoid macular oedema (CMO) secondary to retinal vein occlusions (RVOs). Methods Eyes receiving intravitreal injections for CMO secondary to RVOs that underwent cataract extraction were identified from the Fight Retinal Blindness ...
Alessandro Invernizzi   +12 more
wiley   +1 more source

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