Results 131 to 140 of about 1,883,193 (285)

Association of Localized Retinal Sensitivities with Spectral-Domain Optical Coherence Tomography-Derived Morphologic Data in Macular Subfields in Age-Related Macular Degeneration

Ophthalmic Research
Introduction: This study investigated microperimetry-derived retinal sensitivity and optical coherence tomography (OCT)-based macular morphologic data in eyes with early and intermediate age-related macular degeneration (AMD).
Philipp Anders, Lisa-Marie Anders, Ana Rita Santos, Inês P. Marques, Ana C. Almeida, Stefan Futterknecht, Maximilian Pfau, Katja Hatz, José Cunha-Vaz, Hendrik P.N. Scholl, Conceição Lobo, Rufino Silva, Joaquim N. Murta   +12 more
doaj   +1 more source

Explainable deep learning self‐supervised vision transformer for fundus‐based myopia classification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop and validate a self‐supervised vision transformer (ViT) for automated three‐class classification of Normal, High Myopia (HM), and Pathologic Myopia (PM) from colour fundus photographs, with anatomically faithful interpretability. Methods A DINOv2 self‐supervised ViT was fine‐tuned using a two‐stage transfer‐learning protocol
Eirini Maliagkani, Christos Tsoutsas, Nikolaos Papageorgiou, Ioannis D. Apostolopoulos, Nikolaos Papandrianos, Ilias Georgalas, Elpiniki Papageorgiou   +6 more
wiley   +1 more source

Evaluation of spatial distribution of initial marking strategy among inexperienced graders in diabetic retinopathy: A retrospective cross‐sectional analysis

Acta Ophthalmologica, EarlyView.
Abstract Background Manual diabetic retinopathy (DR) grading may prefer certain regions and underestimate others. It is unclear if inexperienced graders' initial marking strategy reflects a specialist's marking pattern. Aims By the virtual ocular learning platform (VIOLA), we evaluated if initial DR‐lesion markings among inexperienced graders spatially
Simon Joel Ellerup Lowater, Andrea Blasi Núñez, Jakob Kristian Holm Andersen, Sebastian Dinesen, Thiusius Rajeeth Savarimuthu, Jakob Grauslund   +5 more
wiley   +1 more source

Concurrent macular neovascularization in shallow irregular retinal pigment epithelium elevation phenotypes in age‐related macular degeneration and chronic central serous chorioretinopathy: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract This systematic review and meta‐analysis synthesized the reported frequency of concurrent macular neovascularization (MNV) among selected eyes with author‐defined shallow irregular retinal pigment epithelium (RPE) elevations in age‐related macular degeneration (AMD) and chronic central serous chorioretinopathy (CSC).
Mehmet Cem Sabaner, Irem Gunes, Rodrigo Anguita, Elon H. C. van Dijk, Lorenzo Ferro Desideri, Lasse Jørgensen Cehofski, Prithvi Ramtohul, Yousif Subhi   +7 more
wiley   +1 more source

Short pulse grid and subthreshold micropulse laser (the sandwich grid) plus intravitreal ranibizumab for the treatment of diabetic macular edema

International Journal of Retina and Vitreous
Objective To investigate the effects of two laser treatment procedures combined, short pulse grid laser (SP) and subthreshold micropulse laser (MP) (the sandwich grid [SWG] technique), plus intravitreal ranibizumab (IVR) on central subfield thickness ...
Renato Peroni, José Augusto Cardillo, Rafael Memória, Tomas de Oliveira Castro Teixeira Pinto, Lucélia Albieri, Ingrid U. Scott, Rodrigo Jorge   +6 more
doaj   +1 more source

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Low‐level light therapy for dry eye disease and meibomian gland dysfunction: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract A healthy tear film is vital for ocular surface integrity and relies on the coordinated function of the lacrimal glands, meibomian glands and conjunctival goblet cells. Dysfunction in any of these elements can lead to dry eye disease (DED). This systematic review and meta‐analysis evaluated the efficacy of low‐level light therapy (LLLT) as a ...
Sjur Reppe, Yousif Subhi, Tore Steinkjer, Mazyar Yazdani, Miriam Kolko, Tor P. Utheim, Fredrik Andreas Fineide   +6 more
wiley   +1 more source

Higher plasma vitamin D levels are not causally associated with less age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose Higher levels of plasma 25‐hydroxyvitamin D have been associated with a lower risk of age‐related macular degeneration (AMD). We investigated observational and potential causal associations of plasma 25‐hydroxyvitamin D with the risk of AMD in two large contemporary population‐based prospective studies and a genetic case–control ...
Sabina O. Beheshti, Michael Larsen, Børge G. Nordestgaard, Shoaib Afzal   +3 more
wiley   +1 more source

Evaluation of a Digital Amsler Grid (PocDoc) for Macular Disease Screening: A Comparative Analysis with the Conventional Method

Ophthalmology and Therapy
Introduction Macular diseases are major contributors to visual impairment and blindness worldwide. This study introduces PocDoc, a digital version of the conventional Amsler grid, aimed at enhancing the screening and monitoring of macular diseases.
Joewee Boon, William Rojas-Carabali, Yusra Asad, Jonathan Tzien Yih Lim, Rajesh Rajagopalan, Rupesh Agrawal   +5 more
doaj   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source