Results 181 to 190 of about 1,883,193 (285)

Evaluating an AI-assisted triage workflow for retinal diseases. [PDF]

PLOS Digit Health
Park D, Oh R, Baek J, Bae K.
europepmc   +1 more source

Organoids: Current Applications and Future Directions

MedComm, Volume 7, Issue 10, October 2026.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng, Yue Wang, Canhui Cao, Feng Deng, Weisi Lian, Xingtong Chen, Mingmei Lin, Zhonghong Zeng, Dan Mo, Shangqi Li, Yilei He, Yang Yu, Heng Pan, Ping Zhou, Rong Li   +14 more
wiley   +1 more source

EFFICACY AND SAFETY OF AMNIOTIC MEMBRANE TRANSPLANTATION IN VITRECTOMY FOR EXTRA-LARGE OR LONG-STANDING MACULAR HOLES: A Prospective Clinical Study. [PDF]

Retina
Wang Q, Han H, Zhang H, Chen S, Huang Y, Lei Y, Liao M, Zhao P, You C, Yan H.   +9 more
europepmc   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Long-Term Structural and Functional Restoration of the Retina After Inverted Internal Limiting Membrane Flap Surgery for Idiopathic Full-Thickness Macular Holes. [PDF]

Diagnostics (Basel)
Lorenc O, Safranow K, Machalińska A.
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Long-term outcomes of early posterior scleral contraction for myopic macular retinoschisis in patients up to 30 years. [PDF]

Front Med (Lausanne)
Zheng L, Zhao J, Yu C, Dong L, Xue A, Zhu S.   +5 more
europepmc   +1 more source

Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy

MedComm, Volume 7, Issue 10, October 2026.
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu, Mengling You, Yi Zeng, Jinglin Zhang, Si Chen, Rong Rong, Xiaobo Xia   +6 more
wiley   +1 more source

Multimodal Retinal Imaging for the Detection of Early Alzheimer's Disease: Combining Biochemical, Structural, and Vascular Biomarkers. [PDF]

Bioengineering (Basel)
Ghesquiere M, Christinaki E, Lemmens S, Van Eijgen J, Beeckmans L, Ghinis A, Jacobs T, Keer KV, Wehbi Z, De Groef L, Dahdouh-Guebas Y, Charle W, Vande Casteele T, Vandenbulcke M, Vanderlinden G, Laere KV, Schaeverbeke J, Vandenberghe R, Ceccarini J, De Vos M, Stalmans I.   +20 more
europepmc   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source