Results 101 to 110 of about 67,535 (268)

Analysis of Peripapillary and Macular Choroidal Thickness in Eyes with Pseudoexfoliative Glaucoma and Fellow Eyes

Journal of Ophthalmology, 2020
Purpose. To compare differences in peripapillary and macular choroidal thickness in pseudoexfoliative glaucoma (PXG) eyes, nonexfoliative fellow eyes, and normal eyes. Methods. This case-control study included 37 PXG patients (group A: 37 PXG eyes; group
Fan Li, Qingli Shang, Guangxian Tang, Hengli Zhang, Xiaowei Yan, Lihua Ma, Yulei Geng, Qing Zhang   +7 more
doaj   +1 more source

A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head

, 2018
Purpose: To develop a deep learning approach to de-noise optical coherence tomography (OCT) B-scans of the optic nerve head (ONH). Methods: Volume scans consisting of 97 horizontal B-scans were acquired through the center of the ONH using a commercial ...
Aung, Tin, Devalla, Sripad Krishna, Girard, Michael J. A., Perera, Shamira, Pham, Tan Hung, Schmetterer, Leopold, Subramanian, Giridhar, Thiery, Alexandre H., Tun, Tin A., Wang, Xiaofei   +9 more
core   +1 more source

In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]

, 2017
Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David, Farsiu, Sina, Garzel, Laura, Munevar, Christian, Roberts, Jeffrey, Thomasy, Sara, Tieu, Eric, Wong, Brittany, Yiu, Glenn   +8 more
core   +2 more sources

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

Epilepsia Open, EarlyView.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang, Qianqian Zhang, Guangming Li, Lingting Yu, Yanling Ma, Xiaoli Hong, Yujie Kui, Shanshan Cai, Jianguang Sun, Zechao Zhu   +9 more
wiley   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

Microelectromechanical system‐based devices for the diagnosis, treatment, and monitoring of ophthalmic diseases

Interdisciplinary Medicine, EarlyView.
Due to the characteristics of miniaturization, high sensing performance, integration, and high comfort, MEMS‐based devices were employed to design sensors, imaging systems, drug delivery systems, retinal prosthesis, surgical tools, and wearable products for the ophthalmic disease diagnosis, treatment, and monitoring.
Yaling Peng, Xiaoming Huang, Xueyuan Zhang, Yiling Jiang, Xin Zhang, Xueying Zeng, Fengyuan Sun, Peng Liu, Jin Zhou, Zewei Luo, Tong Wu   +10 more
wiley   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

The Impact of Baseline Retinal Volume on Visual Outcomes in the Treatment of Diabetic Macular Edema

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]To assess the effects of initial retinal volume (RV) on visual acuity (VA) after intravitreal bevacizumab treatment for diabetic macular edema (DME).[¤]METHODS[|]The data of 28 eyes of 19 patients treated with bevacizumab for clinically significant diabetic macular edema were retrospectively evaluated in this study. The association
Mümin Hocaoğlu, Mehmet Giray Ersöz, Murat Karaçorlu   +2 more
openaire   +3 more sources

Quantifying Dehydration Effects of Porcine Vocal Fold Attenuation With Optical Coherence Tomography

The Laryngoscope, EarlyView.
The purpose of this study is to use optical coherence tomography (OCT) to characterize the effect of dehydration on the optical attenuation coefficient of porcine vocal fold (VF) tissue. The optical attenuation coefficient tissue decreased linearly with dehydration, dropping by approximately 0.08 mm−1 for every 1% increase in mass loss.
Owen P. Wischhoff, Michael Kuang, Brady D. Prosser, Jakob R. Holm, Jack J. Jiang   +4 more
wiley   +1 more source

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source