Results 171 to 180 of about 450,506 (276)

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin-S Inhibitor, in Healthy Adult Subjects. [PDF]

Clin Transl Sci
Kojima T, Chen W, Smulders R, Stanhope S, Kowalski D, Heo N, Moy S, Goldston A, Han D, Zhu T.   +9 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Better sleep is associated with higher academic performance from an actigraphy-based analysis of sleep consistency and grades in college students. [PDF]

Sci Rep
Lin CT, Liang SF, Shaw FZ.
europepmc   +1 more source

Impact of Ceiling Suspended Shield Size on Primary Operator Radiation Dose During Coronary Angiography and Intervention

Journal of Medical Radiation Sciences, EarlyView.
Reducing radiation exposure to staff performing coronary angiography and intervention is an occupational health and safety priority for hospitals. We demonstrate that a larger lead acrylic shield, with lead rubber pleats on the lower edge will reduce radiation exposure to the cardiologist performing the procedure by approximately 40%. We recommend that
James A. Crowhurst, Elizabeth Andersen, Michael Savage, Jason Tse, Dale Murdoch, Darren Walters, Rustem Dautov   +6 more
wiley   +1 more source

Mitral Annular Disjunction: Case Report and Literature Review. [PDF]

US Cardiol
Ciuciureanu CM, Aten K, Iorgoveanu C.
europepmc   +1 more source

You, Me, and the AI: The Role of Third‐Party Human Teammates for Trust Formation Toward AI Teammates

Journal of Organizational Behavior, EarlyView.
ABSTRACT As artificial intelligence (AI) becomes increasingly integrated in teams, understanding the factors that drive trust formation between human and AI teammates becomes crucial. Yet, the emergent literature has overlooked the impact of third parties on human‐AI teaming.
Türkü Erengin, Roman Briker, Simon B. de Jong   +2 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effects of Single and Multiple Oral Doses of ABP-671 in Healthy and Hyperuricemic Subjects. [PDF]

Drug Des Devel Ther
Gurwith M, Wu RJ, Schwertschlag U, Jin AW, Shi D.   +4 more
europepmc   +1 more source

A Gestalt Therapy Perspective on OCD: A Clinical Case on the “Dance of Reciprocity” Between Therapist and Patient

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This article explores obsessive–compulsive disorder (OCD) through the framework of Gestalt therapy, specifically the “dance of reciprocity” model. It integrates phenomenological, aesthetic, and field‐oriented perspectives. Informed by research on attachment styles and emotional processes in OCD, it provides a developmentally and relationally ...
Margherita Spagnuolo Lobb, Lynne Rigaud, Tomáš Andrášik   +2 more
wiley   +1 more source

Mitral Annular Disjunction Presenting With Ventricular Arrhythmia: A Case Report. [PDF]

Cureus
Taoussi O, Rabii H, Scadi S, Merzouk F, Benouna G.   +4 more
europepmc   +1 more source

Comparing the Last Interglacial (MIS 5e) with the present interglacial period (MIS 1) using a multidimensional functional diversity analysis: The marine molluscs from Santa Maria Island (Azores Archipelago, central Atlantic) as a case study

Journal of Quaternary Science, EarlyView.
ABSTRACT Marine fossil records hold outstanding importance for ecological, evolutionary and biogeographical studies. Santa Maria Island in the Azores Archipelago (central Atlantic) features a remarkable marine fossil record spanning from the Pliocene to recent times.
Sérgio P. Ávila, Samuel Arruda, Luís Silva, Ana Hipólito, Rui Quartau, Ricardo S. Ramalho, Patrícia Madeira, Carlos S. Melo, Lara Baptista, Ana Cristina Rebelo, Gustavo M. Martins, Gonçalo Castela Ávila, Mohamed Amine Doukani, Esther Martín‐González, Daniele Scarponi, Alfred Uchman, Markes Johnson   +16 more
wiley   +1 more source