Results 131 to 140 of about 64,270,038 (288)

Measure for Measure Shakespeare: the Critical Tradition. Volume 6

In this critical evaluation of the classic, the discussion focuses on the nature of the major characters, the morality of their behavior, the conclusion of the play, and the genre of a play that was listed in the First Folio as a comedy.
Geckle, George L.
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The feasibility of using pattern recognition software to measure the influence of computer use on the consultation.

, 2003
Background: A key feature of a good general practice consultation is that it is patient-centred. A number of verbal and non-verbal behaviours have been identified as important to establish a good relationship with the patient.
Alice Theadom, Wilson Eben, Grant, T, Eben Wilson, Dyble, Andy, Tristan Grant, Theadom Alice, Simon de Lusignan, Chan, T, Andy Dyble, de Lusignan Simon, Wilson, E, de Lusignan, S, Theadom, Alice, Dyble Andy, Theadom, A, Grant Tristan, de Lusignan, Simon, Grant, Tristan, Tom Chan, Dyble, A, Chan, Tom, Wilson, Eben, Chan Tom   +23 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

APLICACIÓN DE LOS PRINCIPIOS DEL APRENDIZAJE MOTOR AL ESTUDIO DE LOS NIVELES DE CALIDAD INTERPRETATIVA DE UNA PIEZA MUSICAL CON DOS DIFERENTES TÉCNICAS EN LA GUITARRA CLÁSICA

Publicaciones, 2007
This paper aims to discover suspected differences in the interpretative quality during a performance with a Spanish guitar of a musical piece using two different performance techniques by pressing the strings or not.
Juan Granda Vera, José C. Barbero Alvarez, Natalia Díaz Fernández de Monge   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Made to measure - keeping Rho kinase at a distance. [PDF]

Small GTPases, 2016
Truebestein L, Elsner DJ, Leonard TA.
europepmc   +1 more source

Translating a modern Russian flash animation.

, 2009
Masjanja is a modern Russian cartoon made with Macromedia Flash animation. The translation of Masjanja is a kind of work in progress that improves day by day through the participation of a growing number of people from simple YouTube-users and ...
GALLUCCI, ELEONORA GINA
core