Results 201 to 210 of about 62,455 (285)

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota, Jacy B. Parmera, Matheus Deltreggia, Pedro N. Martins, Anna Letícia M. Alves, Ananda C.M. de Falcone, Ana Rosa Santana, Maria Alice P. Falcão, Mayara A. Dias, Larissa I. Moreira, Paulo C. de Fonseca Filho, Eberval G. Figueiredo, Egberto R. Barbosa, Rubens G. Cury, Daniel C. de Andrade   +14 more
wiley   +1 more source

Who decides on time? Mad Time as a disruptor of normative research politics and practices. [PDF]

Front Sociol
Sinclair A.
europepmc   +1 more source

Timing of Deep Brain Stimulation and Cognitive Trajectories in GBA1‐Associated Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Individuals with Parkinson's disease (PD) carrying GBA1 variants often develop advanced motor complications that prompt evaluation for deep brain stimulation (DBS). However, concerns about accelerated cognitive decline after DBS in GBA1 carriers complicate clinical decision making.
Evridiki Asimakidou, Micol Avenali, Jan O. Aasly, Mitra Afshari, Roy N. Alcalay, Sharlet Anderson, Carlo Alberto Artusi, Bryan Bernard, Marco Bozzali, Susan Bressman, Giovanna Calandra‐Buonaura, Francesco Cavallieri, Roberto Cilia, Jean‐Christoph Corvol, Antoniangela Cocco, Rob M.A. de Bie, Debra Ehrlich, Roberto Eleopra, Thomas Foltynie, Alessio Di Fonzo, Giulia Giannini, Christopher Goetz, Deborah Hall, Joohi Jimenez‐Shahed, Leonardo Lopiano, Vanessa Lythe, Maria Chiara Malaguti, Francesca Mameli, Graziella Mangone, Karen Marder, M. Maral Mouradian, Augusto Rini, Luisa Sambati, Rachel Saunders‐Pullman, Vicki Lynn Shanker, Francesca Spagnolo, Marie‐Laure Welter, Roberta Zangaglia, Gian Pal, Enza Maria Valente, PARKNET Study Group, Giada Cuconato, Ilaria Palmieri, Alberto Imarisio, Pierfrancesco Mitrotti, Francesca Valentino, Claudio Pacchetti, Gabriele Imbalzano, Claudia Ledda, Silvia Gallo, Pietro Cortelli, Luca Baldelli, Ilaria Cani, Raffaella Minardi, Valerio Carelli, Franco Valzania, Edoardo Monfrini, Filippo Cogiamanian, Chiara Longo, Fabiana Colucci, Luigi M. Romito, Marco Liccari   +61 more
wiley   +1 more source

Plasma Lipid Remodeling across Preclinical Burden, Disease Onset, and Early Motor Severity in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background and Objectives Huntington's disease (HD) evolves silently for years before motor onset, yet the systemic metabolic alterations accompanying cumulative exposure to mutant huntingtin and disease progression remain poorly understood.
Mohamed Bendimerad, Dominique Bonneau, Clarisse Scherer‐Gagou, Adriana Prundean, Karim Chikh, Oriane Vitalis, Audrey Olivier, Odile Blanchet, Judith Nzoughet‐Kouassi, Christophe Verny, Pascal Reynier, Juan Manuel Chao de la Barca   +11 more
wiley   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

Mathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang, Yaya Wang, Hongyin Geng, Wei Gao, Esin Ilhan, Haci Mehmet Baskonus   +5 more
wiley   +1 more source

Accelerated Motion‐Compensated Diffusion‐Weighted pCASL Using Subspace Low‐Rank Reconstruction for Quantification of BBB Water Exchange and Permeability

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an accelerated motion‐compensated diffusion‐weighted pseudo‐continuous arterial spin labeling (MCDW‐pCASL) method using a spatial subspace low‐rank reconstruction method for efficient quantification of blood–brain barrier (BBB) water exchange (kw) and permeability (PSw).
Zixuan Liu, Chenyang Zhao, Ziyang Huang, Fanhua Guo, Danny J. J. Wang, Xingfeng Shao   +5 more
wiley   +1 more source

Utica State Hospital: Psychiatric Reform, Institutionalization, and Patient Justice in 19th Century America and Today. [PDF]

Yale J Biol Med
Zhang YV.
europepmc   +1 more source

Improved Upper‐Airway Collapse Imaging in Obstructive Sleep Apnea Using Self‐Supervised Spiral Variational Manifold Learning

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose a self‐supervised variational manifold learning framework for dynamic upper‐airway MRI reconstruction in obstructive sleep apnea from prospectively under‐sampled spiral data during natural sleep, without requiring fully sampled training data.
Md Shahin Ali, Wahidul Alam, Mathews Jacob, Sarv Priya, Douglas Van Daele, Junjie Liu, Sajan Goud Lingala   +6 more
wiley   +1 more source