Results 31 to 40 of about 204,625 (305)
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
SFU Educational Review, 2019 This paper explores a common tension for parents and teachers working with young children – the tantrum. Building on practitioner-inquiry methodologies, I engaged in a living inquiry into my practices as a parent, with the initial goal of reducing or preferably eliminating my son’s angry outbursts.
openaire +2 more sources
Advanced Engineering Materials, EarlyView.This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Molten KNO2 treatment induces a lowrefractive index disordered carbon shell on fluorescent nanodiamonds, enhancing fluorescence emission while preserving spin coherence. Machine learningassisted correlative TEMPL enables direct single‐particle resolution of this enhancement relative to air‐oxidized nanodiamonds of similar morphology, establishing a ...
Parkarsh Kumar +10 more
wiley +1 more source
Démons et déments. Quand Détective enquête sur la folie
Criminocorpus, 2018 This article aims to identify the place of the theme of madness in Detective news magazine. The period of publication of the magazine (1928-1940) by a subsidiary of the publisher Gallimard corresponds to a time when the assistance to the insane is the ...
Marc Renneville
doaj +1 more source
Cardiovascular UltrasoundMitral valve prolapse (MVP) is a common condition affecting approximately 3% of the population, typically with a benign clinical course. However, a small subset of patients (5-10%) may develop severe mitral regurgitation or arrhythmias, which can lead to sudden cardiac death (SCD).
Francesco Fulvio Faletra +10 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
From Don Quixote to Zorba, madness and revolt as an ideology in Mohammad Ghazi’s translations
Cogent Arts & Humanities, 2019 The present article investigates the role of madness in the translated work of a Kurd translator, Mohammad Ghazi (1914–1998) who translated from 1940 to 1998. The aim of the author is discussing the poetics of madness or Revolt in a man who “speaks truth
Diako Ebrahimi
doaj +1 more source