Results 111 to 120 of about 2,191,407 (285)
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann +10 more
wiley +1 more source
ABSTRACT This study presents the first experimental liquid–liquid equilibrium (LLE) data for quaternary systems composed of refined olive pomace oil, oleic acid, ethanol, and water at 303.15 K. These data are essential for the design and optimization of solvent‐based deacidification processes, particularly for oils with high free fatty acid (FFA ...
Jacqueline Mansano Ortega +5 more
wiley +1 more source
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley +1 more source
Configuration of a singular iconography; the venerable doña SanchaAlfonso, comendadora of Santiago
The modern representation of doña Sancha Alfonso, Alfonso IX of León’s daughter and comendadora of theOrder of Santiago, was its right to be in the transfer of its body, in 1608, fromthe oldMonastery of Santa Eufemia (Palencia) to theMonastery of Santa ...
Jesús Ángel Sánchez Rivera
doaj
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli +6 more
wiley +1 more source
Revista de turismo que se publica como órgano oficial de la Sociedad de Atracción de Forasteros, de Madrid, y subvencionada por el Patronato Nacional de Turismo, siendo no venal. Su periodicidad y paginación es variada y es impresa a dos tintas.
core +1 more source
Golondrina : comedia en un acto y en prosa
"Estrenada en el Teatro Lara el 13 de Octubre de 1886"Dedicado a la viuda de PicónLa acción transcurre en Madrid.
Ramos Carrión, Miguel, 1848-1915 +1 more
core
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
Palacios de Madrid : Madrid 2010
ESP
Lasso de la Vega Zamora, Miguel +2 more
openaire +1 more source

