Results 91 to 100 of about 4,566,338 (322)

A Site Evaluation Campaign for a Ground Based Atmospheric Cherenkov Telescope in Romania

, 2010
Around the world, several scientific projects share the interest of a global network of small Cherenkov telescopes for monitoring observations of the brightest blazars - the DWARF network. A small, ground based, imaging atmospheric Cherenkov telescope of
A Konopelko, Ancuta Manea, Aurelian Andrei Radu, Bogdan Lucaschi, Daniel Felea, Dumitru Haşegan, Florin Delia, Ioan Raliţă, Ioana Goia, J Albert, R Koul, Radu Văcăreanu, SC Commichau, Tatiana Angelescu, Valentin Curtef, Vlad Popa   +15 more
core   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

It’s not Magic After All – Machine Learning in Snap! using Reinforcement Learning

2019 IEEE Blocks and Beyond Workshop (B&B), 2019
The societal relevance of artificial intelligence is growing rapidly. Advances are primarily driven by machine learning techniques. Recently, many educational tools for teaching AI have been introduced, allowing the user to implement AI features within ...
Sven Jatzlau, Tilman Michaeli, Stefan Seegerer, R. Romeike   +3 more
semanticscholar   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

Advanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu, Jiaxin Zhang, Xiangyu Yan, Nuo Li, Yu‐Chao Dong, Zihao Wang, Daowei Li, Yong Du, Huan Wang   +8 more
wiley   +1 more source

‘Unremarkable, Forgotten, Cast Adrift’: Feminist Revolutions in Irish Visual Culture

Review of Irish Studies in Europe, 2018
This creative essay examines how visual culture and Alice Milligan’s re-animation of the Tableaux as a radical form of theatre practice operated as a link between ideas of national culture and revolutionary feminism in Ireland. But the tableaux had other
Catherine Morris
doaj   +1 more source

Computer-aided detection of pulmonary nodules in low-dose CT

, 2007
A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical CT images with 1.25 mm slice thickness is being developed in the framework of the INFN-supported MAGIC-5 Italian project.
Delogu, P., Fantacci, M. E., Gori, I., Martinez, A. Preite, Retico, A.   +4 more
core  

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Geohazard features of the Eastern Sardinia

Journal of Maps
The MaGIC project (Marine Geohazard along the Italian Coasts) had the aim of mapping the geohazard in the Italian seas and resulted in numerous maps. In this paper, we present the maps: ‘Maps of Geohazard features of the eastern Sardinian Margin’.
Fabiano Gamberi, Michael Marani, Giacomo Dalla Valle, Marzia Rovere, Elisa Leidi, Alessandra Mercorella, Valentina Ferrante   +6 more
doaj   +1 more source

Marie NDiaye : flou générique et réalisme magique [PDF]

Svět Literatury
The notion of blur will be explored in a short story by Marie NDiaye, Autoportrait en vert, published by Mercure de France. Following the principle of the “Traits et portraits” collection, this book features self-portraits punctuated by illustrations ...
Sylviane Coyault
doaj   +1 more source