Results 101 to 110 of about 465,884 (312)
Texture Evolution of AZ31 Magnesium Alloy Sheet at High Strain Rates
, 2010 In the current contribution the mechanical behaviour at high strain rates of AZ31 magnesium alloy sheet is studied. Uniaxial deformation properties were studied by means of tensile split Hopkinson pressure bar (SHPB) at different temperatures.
Hurtado, I. +9 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Substitution of Ni for Zn on microstructure and mechanical properties of Mg–Gd–Y–Zn–Mn alloy
Journal of Magnesium and Alloys, 2017 This study analyzes the effect of substitution of Ni for Zn on microstructure and mechanical properties of Mg–Gd–Y–Zn–Mn alloy. Our results show that the volume fraction of Mg5(Gd, Y) and (Mg, Zn)3RE phase decreased and LPSO phase increased with more ...
Rongqing Zhang +4 more
doaj +1 more source
Electrolytic MgO/ZrO2 duplex-layer coating on AZ91D magnesium alloy for corrosion resistance
, 2014 Magnesium; SEM; XRD; Electrodeposited films; Oxide coatings; Passive ...
Ching-Fei Li +2 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The uptake of magnesium under exhaustive cropping [PDF]
, 1963 1. A range of soils were cropped exhaustively by perennial rye-grass for up to eleven months in the glasshouse; some were also cropped with Dutch white clover.2.
Arnold, P. W., Salmon, R. C.
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Effect of magnesium on vascular reactivity in NOS inhibition-induced hypertension
, 2015 This study investigated the effect of magnesium on the vascular reactivity of conduit and resistance arteries in a nitric oxide synthase inhibition-induced hypertension model.
Ulker, Seher Nasircilar +6 more
core +1 more source