Results 131 to 140 of about 465,884 (312)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The Effect of Grain Refinement on the Castability of Magnesium-Aluminium Alloys
, 2007 Rapidly increasing fuel prices and global pressures to reduce the harmful effects of vehicle emissions are forcing vehicle manufacturers to look at alternative materials to reduce the mass of the vehicles they produce.
Timothy Kevin Loughnane +1 more
core
Physical metallurgy of magnesium
, 2013 Key features in the deformation behaviour of magnesium have been introduced in terms of the consequences of hexagonal crystal structure, dislocation core width and stacking fault (SF) energy concepts.
A.A. Kaya, Kaya, A. A., Kaya, A.A.
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Magnesium-Based Materials for Energy Conversion and Storage
Journal of Magnesium and Alloys, 2021 Qian Li, Xiaodong Peng, Fusheng Pan
doaj +1 more source
The inhibition effect of etidronate on degradation behavior of Mg–Zn–Y-Nd-Zr alloy
Smart Materials in ManufacturingThe control of corrosion behavior of Mg alloys for biomedical applications is a research hotspot in the field of biodegradable metallic implant materials. In recent years, the employment of corrosion inhibitors for regulating the corrosion behavior of Mg
Di Mei +5 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
CORROSION BEHAVIOUR OF THE AZ31 MAGNESIUM ALLOY AND SURFACE TREATMENTS FOR ITS CORROSION PROTECTION
, 2009 Nowadays environmental conservation forces the transportation industry to manufacture lighter and low emissions transport vehicles. In this contest, magnesium alloys have found increasing attention by the automotive industry because of their low density ...
Zanotto, Federica
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source