ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source
Phase transition of melt-vapor in the magnesium-tin system and its technological application. [PDF]
Volodin V +6 more
europepmc +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel +8 more
wiley +1 more source
Corrosion Behavior and Deterioration Mechanism of Ecological Concrete in Deep Water Environment. [PDF]
Wei H, Wang K, Li C, Chen A, Lu H.
europepmc +1 more source
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah +8 more
wiley +1 more source
Chelation-Driven Self-Assembly of Luminescent Magnesium Coordination Cages. [PDF]
Ouyang N +5 more
europepmc +1 more source
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie +3 more
wiley +1 more source
Interactive Tree Analysis Identifies Dietary Fiber and Magnesium Adequacy as Exploratory Screening Markers for Assessing Nutrient-Dense, Immune-Supportive and Anti-Inflammatory Dietary Patterns in Young Adults Without Comorbidities: Proposition of the New StrongPOLA and RapidPOLA Indexes. [PDF]
Jagielski P +3 more
europepmc +1 more source
Nonlinear relationship between circulating homocysteine and parathyroid hormone among patients with osteoporotic fractures: A cross-sectional study based on a hospital cohort. [PDF]
Wang JH +5 more
europepmc +1 more source

