Results 31 to 40 of about 948,455 (307)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The Edge Crack, Texture Evolution, and Mechanical Properties of Mg-1Al-1Sn-Mn Alloy Sheets Prepared Using On-Line Heating Rolling

Metals, 2018
A series of Mg-1Al-1Sn-Mn magnesium alloy sheets were rolled from 3 mm to 1 mm under temperatures of 150 °C, 200 °C, and 250 °C in four rolling passes using on-line heating rolling.
Qiang Liu, Jiangfeng Song, Fusheng Pan, Jia She, Shuo Zhang, Peng Peng   +5 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Clarifying the influence of albumin on the initial stages of magnesium corrosion in Hank's balanced salt solution

Journal of Magnesium and Alloys, 2021
The corrosion behavior of Mg, a promising biodegradable metallic material, in protein-containing pseudophysiological environment is still not fully understood.
Di Mei, Cheng Wang, Sviatlana V. Lamaka, Mikhail L. Zheludkevich   +3 more
doaj   +1 more source

Maternal and neonatal serum magnesium concentrations in neural tube defects pregnancies in Gorgan (North of Iran) - A case control study [PDF]

, 2010
Objective: Neural tube defects (NTD) comprise a group of congenital malformations that include spinabifida, anencephaly and encephalocele. Previous studies have reported the embryotoxic and teratogenic effects of Magnesium deficiency in animal models ...
Golalipour, M.J., Mansourian, A.R.
core  

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Heterogeneous Phosphotungstate Catalyst Mediated Efficient Alcoholysis of Furfuryl Alcohol into Long-Chain Levulinates

BioResources, 2023
The synthesis of alternative fuels from biomass has emerged to be a vital strategy to maintain sustainable development. Long-chain levulinate esters (LEs) are a class of good biofuel candidates because they have similar structures to biodiesels and ...
Yinghui Wang, Jiao Ma, Qiang Zheng, Yali Ma, Songyan Jia, Xue Li   +5 more
doaj   +2 more sources

Magnesium Disorders [PDF]

New England Journal of Medicine
Contains fulltext : 307615.pdf (Publisher’s version ) (Open Access)
Rhian M. Touyz, Jeroen H.F. de Baaij, Joost G.J. Hoenderop   +2 more
openaire   +2 more sources

Improved magnesia for thermal control coatings [PDF]

, 1972
Formation of radiation-generated color centers using single crystals of magnesium oxide is discussed. Crystal structure of magnesium oxide is described.
Berggren, C. C., Levin, H., Peffley, W. M.   +2 more
core   +1 more source