Results 41 to 50 of about 104,199 (290)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Biocompatibility, Degradation Behavior, and Mechanical Properties of Magnesium Alloy Plates In Vivo

Applied Bionics and Biomechanics, 2023
The magnesium alloy was made into orthopedic steel plates to repair tibial fractures of New Zealand white rabbits and to explore the biocompatibility, degradation behavior, and mechanical properties of the magnesium alloy plates in repairing fractures in
Yongping Wang, Qingqing Qin, Xiaorong Liu, Qiangqiang Li, Huaibin Zhang, Dubin Yang, Yao Jiang   +6 more
doaj   +1 more source

Study of the microstructure, tensile properties and hardness of AZ61 magnesium alloy subjected to severe plastic deformation [PDF]

, 2018
Hot extruded (EX) AZ61 magnesium alloy was processed by the twist channel angular pressing (TCAP) method, which combines equal channel angular pressing (ECAP) and twist extrusion (TE) processes and significantly improves the efficiency of the grain ...
Džugan, Jan, Hilšer, Ondřej, Kraus, Martin, Maziarz, Wojciech, Rusz, Stanislav, Szkandera, Pavel, Čížek, Lubomír   +6 more
core   +1 more source

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

Autopassive Wrought Magnesium Alloys

Advanced Engineering Materials, 2001
Peer ...
Adeva, Paloma, Dodd, S. B., Morgan, P., Hehmann, F., Steinmetz, P., Sommer, F.   +5 more
openaire   +3 more sources

Application of Friction Shear Test for Constitutive Modeling Evaluation of Magnesium Alloy AZ31B at high Temperature [PDF]

, 2020
The experimental determination of the flow stress and its mathematical formulation are essential for the numerical simulation of metal forming processes.
Gensch, Felix, Müller, Sören, Sanabria, Vidal   +2 more
core   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Osteogenesis and degradation behavior of magnesium alloy plate

European Journal of Inflammation, 2021
Introduction: The magnesium alloy was fabricated into orthopedic plates, and used to repair tibial fractures of New Zealand white rabbits. The osteogenesis and degradation behavior of magnesium alloy plates were investigated in vivo . Methods: 38 rabbits
Yongping Wang, Wenqiang Liang, Xiaorong Liu, Qiangqiang Li, Yadong Xie, Yao Jiang   +5 more
doaj   +1 more source

VII.—On the alloys of magnesium [PDF]

J. Chem. Soc.
n ...
openaire   +3 more sources