Results 111 to 120 of about 301,854 (287)

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

open access: yesAdvanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier   +16 more
wiley   +1 more source

Modification‐Selective Inhibition of Succinate Dehydrogenase a Enables Tumor‐Restricted Mitochondrial Modulation

open access: yesAdvanced Science, EarlyView.
This work identifies acetylation‐dependent SDHA homeostasis as a determinant of tumor‐specific metabolic vulnerability. Guided by this mechanism, a modification‐selective inhibitor, ZPI‐3, selectively targets non‐acetylated SDHA, achieving tumor‐restricted SDH inhibition and effective bladder cancer control. Differential responses in clinical specimens
Kaikai Xu   +9 more
wiley   +1 more source

Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats

open access: yes
BACKGROUND: Diabetes, which causes various complications, involves pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), nuclear factor kappa B p65 (NF-κB p65), interleukin-6 (IL-6), cluster of differentiation 4 (CD4), and matrix ...
Bambang Purwanto   +6 more
core   +1 more source

Prothrombin Time Ratio Is Reduced by Magnesium Contamination in Evacuated Blood Collection Tubes

open access: yes, 2001
SummaryMagnesium ions were detected in sodium citrate solutions in several lots of evacuated blood collection tubes. The mean concentrations ranged between 1.3 and 1.6 mmol/L.
W. van Dam   +3 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Pathological conditions caused by magnesium deficiency in women at different ages [PDF]

open access: yesГинекология, 2015
This paper presents a review of publications devoted to the conditions associated with magnesium deficiency in women. Considers the pathological processes occurring in different age and biological periods.
I S Zakharov   +2 more
doaj  

Experiment und Simulation für Fertigungsoptimierung und Einsatzqualifizierung von Magnesium-Bauteilen

open access: yes, 2022
S.175-195Die Strategie der Fraunhofer Allianz "Magnesium Leichtbau" - Orientierung der F und E Arbeiten an industriellen Demonstrator-Bauteilen - Zusammenführung von Herstellung/Technologie mit Bemessung/Bewertung Paralleler Einsatz von experimentellen ...
Blauel, J.G., Götz, T.
core  

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