Results 81 to 90 of about 301,854 (287)

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Prospects for the use of soluble organic magnesium

Медицинский совет, 2015
Correction of magnesium deficiency is an essential component of prevention of many chronic conditions. The highest efficiency of magnesium absorption in the body is ensured by salts, which: 1) are characterized by high solubility and low toxicity, 2) are
O. A. Prokopovich, A. G. Kalacheva, I. Y. Torshin, O. A. Gromova, L. V. Adamyan, O. N. Gracheva   +5 more
doaj   +1 more source

Potassium Magnesium Citrate Is Superior to Potassium Chloride in Reversing Metabolic Side Effects of Chlorthalidone. [PDF]

Hypertension, 2023
Vongpatanasin W, Giacona JM, Pittman D, Murillo A, Khan G, Wang J, Johnson T, Ren J, Moe OW, Pak CCY.   +9 more
europepmc   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

The effect of magnesium citrates on pro-oxidative/antioxidative status in rat liver at experimental diabetes

Біологічні студії, 2016
The activity of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, the content of reduced glutathione and products of lipid peroxidation in liver tissue of rats with alloxan-indused diabetes were investigated.
O. Shatynska, R. Iskra
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

CLINICAL AND BIOCHEMICAL ASPECTS OF THE USE OF MAGNESIUM IN OBSTETRICS, GYNECOLOGY AND PERINATOLOGY

Акушерство, гинекология и репродукция, 2016
Significant biochemical role of magnesium in the body is well-known, as well as good proven clinical efficacy of magnesium in obstetrics and gynecology.
K. Dadak, A. D. Makatsariya, D. V. Blinov, U. V. Zimovina   +3 more
doaj  

ROLE OF MAGNESIUM IN HEADACHE PATHOGENESIS IN CHILDREN AND ADOLESCENTS

Педиатрическая фармакология, 2013
Article is dedicated to the problem of headache in children. This pathology is being found more frequently in pediatric and children’s neurologic practice. The authors examine headache pathogenesis from the position of magnesium deficiency.
E. S. Akarachkova, S. V. Vershinina, O. V. Kotova, I. V. Ryabokon'   +3 more
doaj   +1 more source

Magnesium Citrate Capsules in Colonoscopy Preparation: A Randomized Controlled Trial. [PDF]

Cureus, 2021
Eidensohn Y, Mond Y, Labowitz I, Greenberg P, Formanowski B, Eidensohn C, Dutta S, Dubin E.   +7 more
europepmc   +1 more source

Timeline (Bioavailability) of Magnesium Compounds in Hours: Which Magnesium Compound Works Best?

, 2019
Magnesium is an element of great importance functioning because of its association with many cellular physiological functions. The magnesium content of foods is gradually decreasing due to food processing, and magnesium supplementation for healthy living
Camsari, Ulas M., Kızıldağ, Servet, Yüce, Zeynep, Guvendi, Guven, Kandiş, Sevim, Ateş, Mehmet, Karakilic, Asli, Koç, Talha Başar, Uysal Harzadın, Nazan   +8 more
core   +1 more source