Results 51 to 60 of about 668,027 (272)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

POSTOPERATIVE MAGNESIUM DEFICIENCY

British Journal of Anaesthesia, 1975
Prolonged nasogastric suction and the administration of magnesium-free parenteral fluids produced magnesium deficiency in a patient in the postoperative period. The symptoms of magnesium deficiency are usually overshadowed by those of the primary disease and diagnosis usually rests on the demonstration of low blood concentrations of the ion.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Evaluation of micronutrients among pediatric liver cirrhosis in Shiraz, Iran

Egyptian Liver Journal, 2022
Background Cirrhosis is the final result of most types of liver disease. Zinc, magnesium, and vitamin D have a significantly vital role in the immunologic and physiologic mechanisms in the body.
Seyed Mohsen Dehghani, Anis Amirhakimi, Parisa Baligh, Hazhir Javaherizadeh   +3 more
doaj   +1 more source

The relationship between magnesium deficiency and depression, and the effects of magnesium supplementation on depression symptoms – literature review

Journal of Education, Health and Sport, 2022
Magnesium is a very important macronutrient in the human body. Its main storage is bones. The correct concentration of this macronutrient within the normal range is necessary for the proper functioning of the body.
Dominik Machaj, Alicja Płaczek, Dominik Machaj, Patrycja Baciur, Katarzyna Skowrońska   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Alteration of myocardial mechanics in marginal magnesium deficiency

, 2002
Magnesium has attracted attention as an essential element with diverse roles in the regulation of cardiac contraction. Chronic suboptimal intake of the element results in hypomagnesaemia.

core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Potassium and magnesium deficiency, its role in cardiovascular disease development and possibilities of correction

, 2019
Aim. To evaluate the significance of potassium and magnesium in human health formation and their role in development of functional disorders of cardiovascular and nervous system and in development and progression of cardiovascular diseases.
Olga E. Blokhina, Irina I. Stepanova, Svetlana A. Chorbinskaya, Galina A. Baryshnikova   +3 more
core   +1 more source

The role of magnesium in the treatment of symptoms climacteric syndrome

Медицинский совет, 2019
According to epidemiological studies, about 30% of residents in Russia receive less than 70% of the daily magnesium intake, while magnesium deficiency manifests much more often in women than in men.
A. Z. Khashukoeva, Z. A. Agaeva, M. I. Agaeva, T. N. Sukhova, G. G. Moseshvili, Zh. K. Nurbekova   +5 more
doaj   +1 more source