Results 31 to 40 of about 224,322 (288)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Determination of hydroxyl content in impure magnesium oxide [PDF]
, 1970 Three-step thermal process quantitatively determines the hydroxyl content in samples of magnesium oxide.
Blosser, E. R., Hall, E. H., Iden, R. B.
core +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Isotopically pure magnesium isotope-24 is prepared from magnesium-24 oxide [PDF]
, 1968 Apparatus is used to prepare isotopically pure magnesium isotope-24, suitable for use in neutron scattering and polarization experiments. The apparatus permits thermal reduction of magnesium-24 oxide with aluminum and calcium oxide, and subsequent ...
Chellew, N. R. +2 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The effect of different hydration media on magnesia
Discover Materials, 2021 This paper discusses the rate of hydration of magnesia (CCM1 and CCM2) during the formation of magnesium hydroxide with magnesium acetate and distilled water.
Friedrich von Hoessle +5 more
doaj +1 more source
Magnesium-Containing Slurry as Technogenic Alternative Raw Material for Magnesium Oxychloride Cement [PDF]
, 2019 It has been shown experimentally that a waste of magnesium metal production is a realistic alternative to naturally occurring cement raw materials. The waste is the carnallite slurry forming during the chlorination stage.
Lipunov, I. N., Pervova, I. G.
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Industrial Crops and ProductsTobacco (Nicotiana tabacum L.) is an important cash crop, but its yield, quality, and profitability are severely affected by bacterial wilt caused by Ralstonia solanacearum. There is currently no effective means to control tobacco bacterial wilt.
Han Li +12 more
doaj +1 more source