Results 31 to 40 of about 224,271 (294)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Yttria stabilized zirconia membrane stability in molten fluoride fluxes for low-carbon magnesium production by the SOM process [PDF]
Journal of Mining and Metallurgy. Section B: Metallurgy, 2013 The Solid Oxide Membrane (SOM) process for magnesium production involves the direct electrolysis of magnesium oxide for energy efficient and low-carbon magnesium production.
Milshtein J. +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The effect of different hydration media on magnesia
Discover Materials, 2021 This paper discusses the rate of hydration of magnesia (CCM1 and CCM2) during the formation of magnesium hydroxide with magnesium acetate and distilled water.
Friedrich von Hoessle +5 more
doaj +1 more source
Magnesium-Containing Slurry as Technogenic Alternative Raw Material for Magnesium Oxychloride Cement [PDF]
, 2019 It has been shown experimentally that a waste of magnesium metal production is a realistic alternative to naturally occurring cement raw materials. The waste is the carnallite slurry forming during the chlorination stage.
Lipunov, I. N., Pervova, I. G.
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Industrial Crops and ProductsTobacco (Nicotiana tabacum L.) is an important cash crop, but its yield, quality, and profitability are severely affected by bacterial wilt caused by Ralstonia solanacearum. There is currently no effective means to control tobacco bacterial wilt.
Han Li +12 more
doaj +1 more source
Isotopically pure magnesium isotope-24 is prepared from magnesium-24 oxide [PDF]
, 1968 Apparatus is used to prepare isotopically pure magnesium isotope-24, suitable for use in neutron scattering and polarization experiments. The apparatus permits thermal reduction of magnesium-24 oxide with aluminum and calcium oxide, and subsequent ...
Chellew, N. R. +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source