Results 61 to 70 of about 1,579,866 (269)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Infantile Central Nervous System Juvenile Xanthogranuloma With Somatic CSF1R Mutation Responsive to Imatinib Monotherapy

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Juvenile xanthogranuloma (JXG) of the central nervous system (CNS) is a rare non‐Langerhans cell histiocytosis. CSF1R mutations have been reported for peripheral JXG, but not in CNS JXG. A 3‐month‐old male presented with fever, lymphadenopathy, and macrocephaly with bulging fontanelles.
Sima Vazquez, Kayla Etienne, Long Di, Valerie Martinez‐Torres, Andrew Rosenberg, Sakir H. Gultekin, Aditi Dhir, Bradley Gampel, Heather J. McCrea   +8 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Petrographical and geophysical investigation of the Ecca Group between Fort Beaufort and Grahamstown, in the Eastern Cape Province, South Africa

Open Geosciences, 2019
The outcrop of the Ecca Group in the Eastern Cape Province was investigated in order to reveal petrographic and geophysical characteristics of the formations that make up the group which are vital information when considering fracking of the Karoo for ...
Baiyegunhi Christopher, Nxantsiya Zusakhe, Pharoe Kinshasa, Baiyegunhi Temitope L., Mepaiyeda Seyi   +4 more
doaj   +1 more source

Magnetization arrangement of hard magnetic phases and mechanism of magnetization and reversal magnetization of nano-composite magnets

Transactions of Nonferrous Metals Society of China, 2009
During the process of directional solidification, laser remelting/solidification in the layer on sintered magnets, die-upsetting of cast magnets, or die-upsetting of nano-composites, the arrangements of the easy-magnetization-axes of the hard magnetic phases (Nd2Fe14B, SmCo5 or Sm2Co17 type) in their designed directions have been studied. In Fe-Pt nano-
Xin-cai LIU, Ren XIE, Jing PAN
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Magnetization transfer in magnetic resonance fingerprinting

Magnetic Resonance in Medicine, 2019
PurposeTo study the effects of magnetization transfer (MT, in which a semi‐solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF).MethodsSimulations and phantom experiments were performed to study the impact of MT on the MRF signal and its potential influence on T1 and T2 estimation.
Tom Hilbert, Ding Xia, Kai Tobias Block, Zidan Yu, Riccardo Lattanzi, Daniel K. Sodickson, Tobias Kober, Martijn A. Cloos   +7 more
openaire   +8 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Research on Magnetism and Magnetization Intensity of Magnetic Fluid

Journal of Physics: Conference Series, 2020
Abstract Magnetic fluid is a liquid magnetic material with high magnetization, fluidity and superparamagnetism. The composition and the performance of magnetic fluid in magnetic field were introduced. Magnetic model of magnetic fluid for application was established.
Ruican Hao, Huagang Liu, Zhixin Feng
openaire   +1 more source