Results 171 to 180 of about 3,516 (247)

Machine learning-based prediction of surface quality and tool performance in the grinding of inconel 800. [PDF]

open access: yesSci Rep
Menon RP   +6 more
europepmc   +1 more source

Rhaponticin Blocks Glycolysis‐Mediated Histone Lactylation to Suppress Tongue Squamous Cell Carcinoma via HIF‐1α Activity Inhibition

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma (TSCC) often develops therapeutic resistance. Metabolic reprogramming, particularly the glycolysis/lactate/histone lactylation axis, is a critical driver of tumor progression and therapy resistance. This study investigated the anti‐tumor mechanism of Rhaponticin (Rha), focusing on the metabolic/epigenetic axis ...
Yuan Wu   +7 more
wiley   +1 more source

WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen   +4 more
wiley   +1 more source

Multicenter Study Results on Expanded Indications in Med‐EL Pediatric Cochlear Implant Population

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives To demonstrate safety and efficacy of MED‐EL cochlear implants (CIs) in children aged < 12 months and in children aged 12–71 months with residual hearing. Methods This was a multicenter, nonrandomized, single‐subject, repeated‐measures study with prospective (N = 38; 26 < 12 months of age) and retrospective (N = 209; 70 < 12 months ...
Nancy M. Young   +11 more
wiley   +1 more source

Intrinsically Design‐Rule‐Compliant Nanophotonic Inverse Design via Learned Generative Manifolds

open access: yesLaser &Photonics Reviews, EarlyView.
A generative reparameterization framework for nanophotonic inverse design is introduced, restricting optimization to a learned manifold of design‐rule‐compliant geometries. Unlike conventional penalty‐based approaches, fabrication constraints are encoded intrinsically within the design representation.
Bahrem Serhat Danis   +8 more
wiley   +1 more source

Fretting Wear and Corrosion Behavior of the Fe‐35Mn Biodegradable Alloy for Biomedical Applications

open access: yesMaterials and Corrosion, EarlyView.
This study evaluates the corrosion and tribological wear behavior of the Fe‐35Mn alloy, demonstrating superior mechanical stability and a more favorable degradation rate than pure iron, thereby highlighting its potential for biomedical applications. ABSTRACT The biodegradable Fe‐35Mn alloy has emerged as a promising material for temporary implants due ...
Kerolene Barboza da Silva   +7 more
wiley   +1 more source

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