Results 41 to 50 of about 56,526 (258)

Diagnosis of COVID-19 Using a Deep Learning Model in Various Radiology Domains

Complexity, 2021
Many countries are severely affected by COVID-19, and various casualties have been reported. Most countries have implemented full and partial lockdowns to control COVID-19. Paramedical employee infections are always a threatening discovery.
Yousef Alhwaiti, Muhammad Hameed Siddiqi, Madallah Alruwaili, Ibrahim Alrashdi, Saad Alanazi, Muhammad Hasan Jamal   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Synthetic CT generation for MRI-guided adaptive radiotherapy in prostate cancer

Frontiers in Oncology, 2022
Current MRI-guided adaptive radiotherapy (MRgART) workflows require fraction-specific electron and/or mass density maps, which are created by deformable image registration (DIR) between the simulation CT images and daily MR images.
Shu-Hui Hsu, Zhaohui Han, Jonathan E. Leeman, Yue-Houng Hu, Raymond H. Mak, Atchar Sudhyadhom   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Upen2DTool: A Uniform PENalty Matlab tool for inversion of 2D NMR relaxation data

SoftwareX, 2019
The analysis of Nuclear Magnetic Resonance (NMR) relaxation of 1H nuclei gives fundamental information about the structure of different types of porous media via the determination of 1-dimensional and 2-dimensional (2D) distributions of the typical NMR ...
V. Bortolotti, L. Brizi, P. Fantazzini, G. Landi, F. Zama   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Adaptive testing of Materials using Preisach Model Parameters Variations - Introductory Tests

Advances in Electrical and Electronic Engineering, 2004
A new diagnostic method (MAT - Magnetic Adaptive Testing) for non-destructive testing of ferromagnetic construction materials (i.e. iron based) under mechanical stress is under development, [1]. The method is based on the investigation of the correlation
Elemir Usak, Jan Bydzovsky, Tomas Visnovec   +2 more
doaj  

An alternative 2D ICEEMDAN-based denoising method and its application in processing magnetic anomaly data

Geodesy and Geodynamics
Due to environmental noise and human factors, magnetic data collected in the field often contain various noises and interferences that significantly affect the subsequent data processing and interpretation. Empirical Mode Decomposition (EMD), an adaptive
Jun Xu, Jinsong Du, Changqing Yuan
doaj   +1 more source