Results 31 to 40 of about 46,065 (315)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
LubricantsActive magnetic levitation bearings incorporate backup bearings that support the rotor during a breakdown, allowing it to maintain its circular movement despite the loss of magnetic force.
Jingwei Zhang +4 more
doaj +1 more source
IEEE Access, 2020 Due to the capacity of outputting both the high precision torque and the instantaneous large torque, the vernier-gimballing magnetically suspended flywheel (VGMSFW) is regarded as the key actuator for spacecraft.
Qiang Liu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Superconducting Bearing Design for Outer Rotor Flywheel Using Lumped Parameter Techniques [PDF]
, 2014 This paper describes the application of lumped parameter modeling techniques to designing high temperature superconducting bearings for outer-rotor flywheel energy storage systems.
Chen, D, Longoria, R. G. +2 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Modelling and Experimental Testing of Passive Magnetic Bearings for Power Loss Reduction
Applied SciencesThe development of rotordynamic systems with reduced energy dissipation is a key challenge in modern applications, such as Flywheel Energy Storage Systems.
Alessandro Vigliani +2 more
doaj +1 more source
Vibration reduction in a hollow-shaft rotor using flexibly-mounted internal-stator magnetic bearings
Mechanical Engineering Journal, 2017 A topology composed of a hollow-shaft rotor on rolling element bearings coupled with internal-stator magnetic bearings mounted on independently supported flexible shafts is considered for the purposes of vibration reduction. Details of a bespoke test rig
Christopher LUSTY, Patrick KEOGH
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Suppression of Base Excitation of Rotors on Magnetic Bearings
International Journal of Rotating Machinery, 2007 This paper deals with rotor systems that suffer harmonic base excitation when supported on magnetic bearings. Magnetic bearings using conventional control techniques perform poorly in such situations mainly due to their highly nonlinear characteristics ...
Steven Marx, C. Nataraj
doaj +1 more source