Results 61 to 70 of about 1,953,891 (241)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Development of a Sensitive Induction-Based Magnetic Nanoparticle Biodetection Method

open access: yesNanomaterials, 2018
We developed a novel biodetection method for influenza virus based on AC magnetic susceptibility measurement techniques (the DynoMag induction technique) together with functionalized multi-core magnetic nanoparticles.
Jakob Blomgren   +9 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

The Browning Circle Constitution

open access: yes, 1891
The Browning Circle Constitution is the document used to create and govern the Athens Browning Circle.  It lists the by-laws as they were followed in 1891https://digitaltennessee.tnsos.gov/egfisher_browning_circle_docs/1001/thumbnail ...
Browning Circle Library
core   +1 more source

Supersymmetric dyonic strings in 6-dimensions from 3-dimensions

open access: yesJournal of High Energy Physics, 2019
It was shown in arXiv:1410.7168 that compactifying D = 6, N = 1 0 $$ \mathcal{N}=\left(1,0\right) $$ ungauged supergravity coupled to a single tensor multiplet on S3 one gets a particular D = 3, N = 4 $$ \mathcal{N}=4 $$ gauged supergravity which is a ...
Nihat Sadik Deger   +2 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Non Linear Proper Generalized Decomposition method applied to the magnetic simulation of a SMC microstructure [PDF]

open access: yes, 2012
Improvement of the magnetic performances of Soft Magnetic Composites (SMC) materials requires to link the microstructures to the macroscopic magnetic behavior law.
CLENET, Stephane   +2 more
core   +1 more source

Cerebrovascular ischemic changes associated with fetal posterior cerebral artery- descriptive retrospective study with magnetic resonance imaging and angiography of brain [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2016
Objectives: Circle of Willis, the main collateral pathway for cerebral circulation, is complete in only a portion of the population. There are many variations in the Circle of Willis.
Venkatraman Indiran   +1 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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