Results 91 to 100 of about 11,654,333 (303)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Hybrid torque and SQUID magnetometry of individual magnetic nanotubes [PDF]

, 2015
For the experiments presented in this thesis, a hybrid magnetometer consisting of a ultra sensitive Si cantilever and a nano-scale superconducting quantum interference device (nanoSQUID) sensitive enough to measure a single nanoscale magnetic particle ...
Buchter, Arne
core   +1 more source

Controllability and control synthesis of underactuated magnetic microrobots

Automatica, 2023
The control of multiple magnetic microrobots is of particular interest for therapeutic applications. Yet the controllability of such a system is not straightforward since, on most of such systems designs, there is only a single control input per axis.
openaire   +4 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Active Magnetic Bearings for Frictionless Rotating Machineries [PDF]

, 2006
Active magnetic bearing (AMB) systems can support a rotor without physical contact and enable users to precisely control rotor position and vibration as function of time or other parameters.
SETIAWAN, Joga Dharma
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Real-time plasma equilibrium reconstruction and shape control for the MAST Upgrade tokamak

Nuclear Fusion
Real-time magnetic control has been developed to deliver precise control of multiple plasma shape parameters for advanced divertor configurations, including double-null, Super-X, X-point target and X-divertor for the first time on the MAST Upgrade (MAST ...
H. Anand, W. Wehner, D. Eldon, A. Welander, Z. Xing, A. Lvovskiy, J. Barr, E. Cho, B. Sammuli, D. Humphreys, N. Eidietis, A. Leonard, M. Kochan, C. Vincent, G. McArdle, G. Cunningham, A. Thornton, J. Harrison, V. Soukhanovskii, J. Lovell   +19 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Propulsion of Planar V‐Shaped Microswimmers in a Conically Rotating Magnetic Field

Advanced Intelligent Systems
Planar magnetic microswimmers bear great potential for in vivo biomedical applications as they can be mass‐produced at minimal costs using standard photolithography techniques. Therefore, it is central to understand how to control their motion.
Yasin Cagatay Duygu, U Kei Cheang, Alexander M. Leshansky, Min Jun Kim   +3 more
doaj   +1 more source