Results 71 to 80 of about 1,019,438 (296)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Magnetic core current steering commutator Patent [PDF]
, 1970 Describing magnetic core current switching device for steering bipolar current pulses to memory ...
Zottarelli, L. J.
core +1 more source
, 2013 The energy of magnetic vortex core and its equilibrium radius in thin circular cylinder were first presented by N.A. Usov and S.E. Peschany in 1994. Yet, the magnetostatic function, entering the energy expression, is hard to evaluate and approximate.
Aharoni +18 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Collapse of Rotating Magnetized Molecular Cloud Cores and Mass Outflows
, 2001 Collapse of the rotating magnetized molecular cloud core is studied with the axisymmetric magnetohydrodynamical (MHD) simulations. Due to the change of the equation of state of the interstellar gas, the molecular cloud cores experience several different ...
Bentz W. +18 more
core +2 more sources
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
EnergiesElectromagnetic field analysis and loss calculation is crucial for designing and optimizing magnetic components in high-frequency applications. The traditional method of combining eddy current field equations with hysteresis models is often used for low ...
Chengbo Li, Ming Cheng, Wei Wang
doaj +1 more source
Effects of Resistivity on Magnetized Core-Collapse Supernovae
, 2013 We studied roles of a turbulent resistivity in the core-collapse of a strongly magnetized massive star, carrying out 2D-resistive-MHD simulations.
Kotake, Kei +3 more
core +1 more source