Results 131 to 140 of about 1,531 (255)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Three-Dimensional Assessment of Charcot Neuroarthropathy Deformities: Comparison of Standard 2D vs Patient-Specific 3D Measurements. [PDF]

Foot Ankle Int
Chopra AA, Koroneos ZA, Pitcher MD, Benedict C, Tortora P, Lan T, Levidy M, Kunselman A, Aynardi M.   +8 more
europepmc   +1 more source

Mapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS

Advanced Healthcare Materials, EarlyView.
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph, Maria Rosa Gigliobianco, Cristina Minnelli, Paolo Moretti, Francesco Spinozzi, Giovanna Mobbili, Sara Pistolesi, Cristina Casadidio, Gabriella Teti, Roberta Censi, Stefano Antonio Gattone, Piera Di Martino   +11 more
wiley   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source

Middle Pleistocene tectonic events around the SE Aegean Sea: Insights from magnetostratigraphy, (U-Th)/He zircon dating, and fault kinematics in the Datça Graben (SW Türkiye). [PDF]

Sci Rep
İnce MD, Kaymakci N, Langereis C, Uzel B, Gülyüz E, Koralay EO, Stoica M, Sümer Ö.   +7 more
europepmc   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission. [PDF]

Space Sci Rev
Christian ER, Mitchell JG, Bruno A, Albaijes D, Bailey Newman S, Boggs RC, Choi MK, Cohen CMS, Cook WR, Darwish YS, Davis AJ, de Nolfo GA, Dumonthier JJ, Garnett RD, Gkioulidou M, Gregory KJ, Guzman Garcia D, Haas JP, Hollenhorst C, Jeunon M, Kaiser MA, Kanekal SG, Kecman B, Leske RA, Letzer JD, Liceaga Indart I, McComas DJ, McNeel B, Muro GD, Nolan JT, Ogindo M, Petrowich P, Reaves WJ, Rosnack TP, Saghafi N, Salerno CL, Schwadron NA, Silber MA, Smith ES, Smith MT, Suárez G, Tatoli T, Tiu CP, Wiedenbeck ME, Windhausen MH, Xu Z.   +45 more
europepmc   +1 more source

The Discovery of Magnetic Declination [PDF]

Nature, 1906
openaire   +1 more source

Ultrasound‐Triggered Nanobubbles for Endothelial‐Targeted Drug Delivery in the Detection and Treatment of Doxorubicin‐Induced Cardiotoxicity

Advanced Healthcare Materials, EarlyView.
The DA/VTP‐NBs selectively recognized cardiac ECs damaged by DIC and achieved cell‐level targeted imaging. Then US‐triggered controlled release successfully enabled the release of DAPA within the DA/VTP‐NBs at the site of injury. This precise on‐demand drug release approach amplifies a series of localized therapeutic effects through the mtDNA‐mediated ...
Jun Zhang, Yi Ling, Xin Li, Deng Liu, Li Dong, Xuemei Chen, Yingxin Sun, Yongning Shang, Yanli Guo   +8 more
wiley   +1 more source

Scanning Magnetic Microscopy Using a High-Sensitivity Room-Temperature Tunnel Magnetoresistance Sensor for Geological Applications. [PDF]

Sensors (Basel)
Oda H, Fujiwara K, Fukuyo N, Kubota H, Ichinose T, Oogane M, Kumagai S, Matsuzaki H, Uchida T, Kawabata M, Kawai J.   +10 more
europepmc   +1 more source