Results 81 to 90 of about 24,442 (290)
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Contributions to Geophysics and GeodesyThe recently proposed dayside current wedge likely explains the mechanism behind the well-known Carrington geomagnetic storm on 2 September 1859, as well as an event observed in Europe on 29 October 2003. Both events were swift and intense, had unusually
Eduard KOČI, Fridrich VALACH
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem +17 more
wiley +1 more source
Anisotropy of TeV Cosmic Rays and the Outer Heliospheric Boundaries
, 2012 Cosmic rays in the energy range from about 10's GeV to several 100's TeV are observed on Earth with an energy-dependent anisotropy of order 0.01-0.1%, and a consistent topology that appears to significantly change at higher energy.
Desiati, P., Lazarian, A.
core +1 more source
Young stellar object jet models: From theory to synthetic observations [PDF]
, 2013 Astronomical observations, analytical solutions and numerical simulations have provided the building blocks to formulate the current theory of young stellar object jets.
Cayatte, V. +11 more
core +6 more sources
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Estimating the extremes in European geomagnetic activity [PDF]
, 2009 Rapidly changing geomagnetic field variations constitute a natural hazard, for example in navigation and, through geomagnetically induced currents, to power grids and pipeline networks.
Dawson, Ewan, Reay, Sarah, Thomson, Alan
core
Search for Anisotropy of Ultra-High Energy Cosmic Rays with the Telescope Array Experiment [PDF]
, 2012 We study the anisotropy of Ultra-High Energy Cosmic Ray (UHECR) events collected by the Telescope Array (TA) detector in the first 40 months of operation.
A. L. Sampson +159 more
core +2 more sources
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source