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Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Effect of Gradient Heat Conduction on Secondary Recrystallization of Grain-Oriented Silicon Steel
The grain-oriented silicon steels were subjected to gradient heat conduction during high-temperature annealing by using thermal insulation cotton. The macrostructures of samples subjected to circumferential gradient heat conduction showed a “petal-like ...
Qian Gao +5 more
doaj +1 more source
Current-induced domain wall motion in a nanowire with perpendicular magnetic anisotropy
We study theoretically the current-induced magnetic domain wall motion in a metallic nanowire with perpendicular magnetic anisotropy. The anisotropy can reduce the critical current density of the domain wall motion. We explain the reduction mechanism and
Jung, Soon-Wook +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Electric field control of magnetization reversal in FeGa/PMN-PT thin films
Artificial magnetoelectric materials possess huge potential to be utilized in the development of energy efficient spintronic devices. In the past decade, the search for a good ferromagnetic/ferroelectric combination having the ability to create high ...
Gajanan Pradhan +6 more
doaj +1 more source
The evolution of magnetic domain structure in epitaxial La$_{0.625}$Ca$_{0.375}$MnO$_3$ films on (001) NdGaO$_3$ is monitored as a function of temperature and magnetic field using Magnetic Force Microscopy.
Budhani, R. C. +3 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Electroinduced magnetic bubble domain nucleation
The magnetoelectric properties of micromagnetic structures in iron garnet films manifest themselves in electrically induced displacement of domain walls and magnetic bubble domains nucleation.
Kulikova Daria +3 more
doaj +1 more source
Multiple Walker breakdowns in magnetic multilayers
Herein, we report an exotic domain-wall dynamics showing double Walker breakdowns in magnetic multilayer films composed of two magnetic layers. Such multiple Walker breakdowns are attributed to the internal magnetic dipole field, which is antisymmetric ...
Joon Moon +5 more
doaj +1 more source

