Results 41 to 50 of about 504,040 (288)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Magnetostrictive hysteresis of TbCo/CoFe multilayers and magnetic domains
Magnetic and magnetostrictive hysteresis loops of TbCo/CoFe multilayers under field applied along the hard magnetization axis are studied using vectorial magnetization measurements, optical deflectometry and magneto optical Kerr microscopy.
A. Thiaville +10 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The accurate characterization of local magnetic fields and temperature is vital for the design of electronic systems. To meet this imperative, we present a novel non-contact approach for simultaneous quantitative magnetic field imaging and temperature ...
Michael P. Path, Jeffrey McCord
doaj +1 more source
Magnetic Properties of Fe-Si Electrical Steel after Laser Scribing [PDF]
Improvement of magnetic properties of electrical steel can be achieved by reduction the size of magnetic domains. The application of local stresses through laser scribing leads to reduced core losses.
K. Ścibisz, J. Krawczyk
doaj +1 more source
The influence of magnetic anisotropy on nanosecond magnetization reversal in coupled FeNi/Cu/Co trilayers was studied using a photoelectron emission microscope combined with x-ray magnetic circular dicroism. In quasi-isotropic samples the reversal of the
A. A. Thiele +12 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Impedance Modeling of Magnetometers: A Path Toward Low-Noise Readout Circuits
Optimizing sensor readout schemes and integrated circuit designs for both open-loop and closed-loop implementations requires precise modeling and simulation strategies.
Arbustini Johan +9 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
On the Origin of Signal and Bandwidth of Converse Magnetoelectric Magnetic Field Sensors
Converse magnetoelectric sensors enable the detection of low‐frequency and low‐amplitude magnetic fields over a bandwidth of several kilohertz by combining the electrical excitation of a magnetoelectric resonator via a piezoelectric layer with an ...
Elizaveta Spetzler +9 more
doaj +1 more source

