Results 151 to 160 of about 3,189,782 (241)

The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta, Augusto J. Mendes, Valentina Garibotto, Cecilia Boccalini, Aurelien Lathuiliere, Innocenzo Rainero, Elisa Rubino, Henrik Zetterberg, Nicholas J. Ashton, Federica Ribaldi, Giovanni B. Frisoni, for the Alzheimer's Disease Neuroimaging Initiative   +11 more
wiley   +1 more source

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter, Hans Dorn, Julian Hellmann‐Regen, Ana Bueno‐Lopez, Verena van Ginneken, Heidi Danker‐Hopfe   +5 more
wiley   +1 more source

Doped Ferrite Nanoparticles Exhibiting Self-Regulating Temperature as Magnetic Fluid Hyperthermia Antitumoral Agents, with Diagnostic Capability in Magnetic Resonance Imaging and Magnetic Particle Imaging. [PDF]

Cancers (Basel), 2022
Vurro F, Gerosa M, Busato A, Muccilli M, Milan E, Gaudet J, Goodwill P, Mansfield J, Forlin E, Negri A, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Wintermark M, Speghini A, Marzola P.   +16 more
europepmc   +1 more source

Improving the Diagnostic Accuracy of Plasma Alzheimer's Disease Biomarkers With Objective and Subjective Cognitive Screening

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki, Leslie S. Gaynor, Dandan Liu, Timothy J. Hohman, Katherine A. Gifford, Henrik Zetterberg, Angela L. Jefferson, Corey J. Bolton   +7 more
wiley   +1 more source

Biosafety of micron-sized Fe₃O₄ magnetic fluid for pulmonary injection: a preclinical study toward lung nodule localization. [PDF]

J Thorac Dis
Lv X, Xu H, Zhang Z, Wang T, Yu C, Liu S, Yang R, Yang Z, Liang R, Li C, Liu A, Ahmed AWH, You J, Li Y, Li Y, Zhang Y.   +15 more
europepmc   +1 more source

Magnetic Fluid Hyperthermia as Treatment Option for Pancreatic Cancer Cells and Pancreatic Cancer Organoids. [PDF]

Int J Nanomedicine, 2021
Palzer J, Mues B, Goerg R, Aberle M, Rensen SS, Olde Damink SWM, Vaes RDW, Cramer T, Schmitz-Rode T, Neumann UP, Slabu I, Roeth AA.   +11 more
europepmc   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu, Peng Guo, Rui Pan, Zhenghao Wang, Jingchao Zhou, Pengcheng Zhang, Xingzhe Zhang, Qinghua Zhang, Haibin Ma, Zhanfeng Niu   +9 more
wiley   +1 more source

Magnetic Fluid-Driven Vine Robots for Minimally Invasive Tissue Biopsy Sampling. [PDF]

Adv Intell Syst
Davy J, Dean TP, Greenidge NJ, Calmé B, Lloyd P, Chandler JH, Valdastri P.   +6 more
europepmc   +1 more source

Application of Mn _x Fe_1-x Fe₂O₄ (x = 0-1) Nanoparticles in Magnetic Fluid Hyperthermia: Correlation with Cation Distribution and Magnetostructural Properties. [PDF]

ACS Omega, 2022
Phalake SS, Lad MS, Kadam KV, Tofail SAM, Thorat ND, Khot VM.   +5 more
europepmc   +1 more source

Serostatus‐Specific Prognostic Profiles and Phenotype‐Dependent Therapeutic Windows in Autoimmune Encephalitis: A Multicenter Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background While autoimmune encephalitis (AE) outcomes vary, serostatus‐specific prognostic determinants and institutional clustering effects remain poorly characterized. We aimed to delineate the distinct prognostic architecture of AE, identifying serostatus‐specific risk factors and potential therapeutic windows.
Xiaohong Tang, Jingxian Wang, Kaixin Zhu, Zhen Zhang, Liao Wu, Wei Wang, Chang Li, Qingyun Li, Hao Li, Jinghua Chen, Zhangxu Lian, Bin Liu, Tengfei Liu, Chunmei Wen, Nuan Wang, Sen Qun, Lishun Xiao, Qingwei Lai   +17 more
wiley   +1 more source