Results 41 to 50 of about 80,347 (262)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Magnetic tweezers with magnetic flux density feedback control [PDF]
Review of Scientific Instruments, 2020 In this work, we present a single-pole magnetic tweezers (MT) device designed for integration with substrate deformation tracking microscopy and/or traction force microscopy experiments intended to explore extracellular matrix rheology and human epidermal keratinocyte mechanobiology.
Waddah I. Moghram +3 more
openaire +2 more sources
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FLUX EMERGENCE IN A MAGNETIZED CONVECTION ZONE [PDF]
The Astrophysical Journal, 2013 Accepted for publication in ...
Pinto, R.F., Brun, A.S.
openaire +3 more sources
Numerical Simulation of Solar Magnetic Flux Emergence Using the AMR–CESE–MHD Code
The Astrophysical Journal Supplement Series, 2022 Magnetic flux emergence from the solar interior to the atmosphere is believed to be a key process in the formation of solar active regions and driving solar eruptions.
Zhipeng Liu +4 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Reconnection of magnetic flux ropes driven by two-color Laguerre–Gaussian laser pulses in plasma
Matter and Radiation at ExtremesThe generation and reconnection of magnetic flux ropes in a plasma irradiated by two Laguerre–Gaussian laser pulses with different frequencies and opposite topological charges are investigated numerically by particle-in-cell simulations. It is shown that
Yin-Hong Liu +2 more
doaj +1 more source
An Improved Seeding Algorithm of Magnetic Flux Lines Based on Data in 3D Space
Data Science Journal, 2015 This paper will propose an approach to increase the accuracy and efficiency of seeding algorithms of magnetic flux lines in magnetic field visualization. To obtain accurate and reliable visualization results, the density of the magnetic flux lines should
Jia Zhong, Xiaoyan Hu, Ziming Zou
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source