Results 41 to 50 of about 45,930 (257)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Feasibility Study of Stress Measurement in Prestressing Tendons Using Villari Effect and Induced Magnetic Field

International Journal of Distributed Sensor Networks, 2013
This paper investigates experimentally the feasibility of estimating the stress in the prestressing tendons of prestressed concrete bridges using the magnetic field induced by an electromagnet and the Villari effect in which the magnetic susceptibility ...
Changbin Joh, Jung Woo Lee, Imjong Kwahk
doaj   +1 more source

Influence of Permanent Magnetic Properties on Laser-Assisted Heating Magnetization for Magnetic MEMS

IEEE Access, 2023
When magnetic microelectromechanical systems (MEMS) devices utilize thin- or thick-film permanent magnets, the uniform magnetization of these magnets, owing to their flat-shape, generate a strong antimagnetic field and weak surface magnetic flux density.
Keita Nagai, Naohiro Sugita, Tadahiko Shinshi   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

High Performance Planar Magnetics Based on an Unbalanced-Flux Approach

IEEE Open Journal of Power Electronics, 2023
This paper presents a new design concept to increase the efficiency and the power density of planar magnetics. In contrast to the existing magnetics, which are built using the balanced magnetic flux density design, the proposed design concept generates ...
Sobhi Barg, Souhaib Barg, Kent Bertilsson   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Magnetic Flux Emission from Extremely Low Frequency Electromagnetic Fields around High Voltage Power Transmission Lines

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Considerable increase on the use of electronic devices increased the rate of public occupational exposure to extremely low frequency electromagnetic fields.
Mohammad Ali Zazouli, Mahmoud Mohammadyan2, Seyed Noroddin Mousavinasab, Mostafa Mohajer Darabi, Adele Sarem Safari   +4 more
doaj  

An Improved Seeding Algorithm of Magnetic Flux Lines Based on Data in 3D Space

Data Science Journal, 2015
This paper will propose an approach to increase the accuracy and efficiency of seeding algorithms of magnetic flux lines in magnetic field visualization. To obtain accurate and reliable visualization results, the density of the magnetic flux lines should
Jia Zhong, Xiaoyan Hu, Ziming Zou
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source