Results 41 to 50 of about 3,463,479 (362)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Monopole production via photon fusion and Drell–Yan processes: MadGraph implementation and perturbativity via velocity-dependent coupling and magnetic moment as novel features [PDF]

The European Physical Journal C, 2018
In this work we consider point-like monopole production via photon-fusion and Drell–Yan processes in the framework of an effective U(1) gauge field theory obtained from conventional models describing the interaction of spin magnetically-charged fields ...
S. Baines, N. Mavromatos, V. Mitsou, J. Pinfold, A. Santra   +4 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Magnetized target fusion and fusion propulsion [PDF]

AIP Conference Proceedings, 2002
Magnetized target fusion (MTF) is a thermonuclear fusion concept that is intermediate between the two mainline approaches, magnetic confinement and inertial confinement fusion (MCF and ICF). MTF incorporates some aspects of each and offers advantages over each of the mainline approaches.
openaire   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Plasma heat load in the toroidal gaps of the ITER-like plasma facing units in WEST tokamak

Nuclear Materials and Energy
The heat load deposited in the toroidal gaps between two tungsten monoblocks remains an open problem to prepare safe and powerful experiments in ITER.
Q. Tichit, M.H. Aumeunier, Y. Corre, R. Dejarnac, L. Dubus, J. Gaspar, J. Gerardin, A. Grosjean, J.P. Gunn, A. Juven, K. Krieger, A. Podolník, E. Tsitrone   +12 more
doaj   +1 more source

Understanding the spectrum during the tearing mode locking by rotating RMP in J-TEXT

AIP Advances, 2022
The rotating resonant magnetic perturbation (RMP) could lock the tearing mode (TM) and prevent disruption. It is found that the TM instantaneous frequency oscillates during TM locking on the RMP.
Da Li, Mao Li, Yonghua Ding, Nengchao Wang, Bo Rao, Ying He, Feiyue Mao, Chengshuo Shen, Ruo Jia, Song Zhou, Zhengkang Ren, Chuanxu Zhao, Abba Alhaji Bala, Zhipeng Chen, Zhongyong Chen, Zhoujun Yang, Lin Yi, Kexun Yu, J-TEXT Team   +18 more
doaj   +1 more source

Properties of soft magnetic Fe-Co-V alloy produced by laser powder bed fusion

Rapid prototyping journal, 2019
Purpose The purpose of this paper is to report on the developments in manufacturing soft magnetic materials using laser powder bed fusion (L-PBF). Design/methodology/approach Ternary soft magnetic Fe-49Co-2V powder was produced by gas atomization and ...
Tuomas Riipinen, S. Metsä-Kortelainen, T. Lindroos, Janne S. Keränen, Aino Manninen, Jenni Pippuri-Mäkeläinen   +5 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Dividing and setting strategy of improving calculation efficiency for needle electrode corona discharge with a large‐scale space

High Voltage, 2022
Needle electrodes are widely used in the research of corona discharge. Aiming at the problem of needle electrode discharge in a large‐scale space (tens or even hundreds of centimetres), a hybrid model was proposed in the previous work.
Dingchen Li, Chuan Li, Jiawei Li, Pengyu Wang, Zhi Liu, Wendi Yang, Ming Zhang, Yong Yang, Kexun Yu   +8 more
doaj   +1 more source