Results 41 to 50 of about 5,149,918 (310)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A New Approach Integrated Magnetics Double-Frequency DC/DC Converter

open access: yesIEEE Access, 2020
Double-frequency DC/DC converter can improve switching frequency and reduce switching loss than single-frequency DC/DC converter. However, it is heavy and large due to its small high-frequency inductor and large low-frequency inductor.
Shengwei Gao, Hao Wang
doaj   +1 more source

Faraday effect in CoPt-CaF2 nanogranular films with hard magnetic property for magnetic-field-free faraday devices

open access: yesFrontiers in Physics, 2022
Magneto-optical Faraday devices, such as optical isolators, require a structure to apply a magnetic field to the incorporated magneto-optical material.
Nobukiyo Kobayashi   +3 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Cortical plasticity of audio-visual object representations [PDF]

open access: yes, 2009
Several regions in human temporal and frontal cortex are known to integrate visual and auditory object features. The processing of audio–visual (AV) associations in these regions has been found to be modulated by object familiarity.
Döhrmann, Oliver   +17 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Magnetic Integration Applied to an Isolated Single-Stage AC–DC Converter

open access: yesIEEE Open Journal of Power Electronics
This work proposes a novel magnetic integration approach applied to a four-leg interleaved single-phase ac-dc converter topology, aimed at minimizing component count and increasing power density.
Samanta Gadelha Barbosa   +4 more
doaj   +1 more source

Oscillating magnetic field disrupts magnetic orientation in Zebra finches, Taeniopygia guttata [PDF]

open access: yes, 2009
Background Zebra finches can be trained to use the geomagnetic field as a directional cue for short distance orientation. The physical mechanisms underlying the primary processes of magnetoreception are, however, largely unknown.
Wiltschko, Wolfgang   +20 more
core   +1 more source

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