Results 51 to 60 of about 237,895 (266)

Magnetic nanochain integrated microfluidic biochips [PDF]

Nature Communications, 2018
AbstractMicrofluidic biochips hold great potential for liquid analysis in biomedical research and clinical diagnosis. However, the lack of integrated on-chip liquid mixing, bioseparation and signal transduction presents a major challenge in achieving rapid, ultrasensitive bioanalysis in simple microfluidic configurations.
Qirong Xiong, Chun Yee Lim, Jinghua Ren, Jiajing Zhou, Kanyi Pu, Mary B. Chan-Park, Hui Mao, Yee Cheong Lam, Hongwei Duan   +8 more
openaire   +4 more sources

Magnetic Integration Applied to an Isolated Single-Stage AC–DC Converter

IEEE Open Journal of Power Electronics
This work proposes a novel magnetic integration approach applied to a four-leg interleaved single-phase ac-dc converter topology, aimed at minimizing component count and increasing power density.
Samanta Gadelha Barbosa, Jose Willamy Medeiros de Araujo, Jens Friebe, Fernando Lessa Tofoli, Demercil de Souza Oliveira   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Integrated Planar Transformer for High-Voltage-Ratio LLC DCX With High Current and Ultra-Low Voltage Output

IEEE Open Journal of Power Electronics
The 48 V voltage regulation modules (VRM) for microprocessors feature a high voltage transformation ratio, large current, and ultra-low voltage output. The solutions based on high-turns-ratio transformers are the most popular ones.
Kangping Wang, Yuhang Ning, Hongchang Li, Xu Yang   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Machine learning reveals orbital interaction in materials

Science and Technology of Advanced Materials, 2017
We propose a novel representation of materials named an ‘orbital-field matrix (OFM)’, which is based on the distribution of valence shell electrons. We demonstrate that this new representation can be highly useful in mining material data.
Tien Lam Pham, Hiori Kino, Kiyoyuki Terakura, Takashi Miyake, Koji Tsuda, Ichigaku Takigawa, Hieu Chi Dam   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The boundary integral method for magnetic billiards [PDF]

Journal of Physics A: Mathematical and General, 2000
28 pages, 12 ...
Hornberger, K., Smilansky, U.
openaire   +3 more sources

Stackless Onboard Coil for Dynamic Wireless Power Transfer

IEEE Open Journal of Power Electronics
Dynamic wireless power transfer (DWPT) technology is emerging as a key enabler for in-motion charging of electric vehicles (EVs), allowing continuous energy transfer without the need for dedicated charging stops.
Shuntaro Inoue, Koki Sasai, Norika Miura, Koji Shigeuchi, Masato Maemura, Toshiya Hashimoto, Hayato Sumiya, Masaya Takahashi, Eisuke Takahashi, Nobuhisa Yamaguchi   +9 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source