Results 61 to 70 of about 7,536,747 (258)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Immunomodulation of Patients with Canine Visceral Leishmaniasis at Different Stages: A 12-Month Follow-Up Study Using LaSap

Vaccines
Background/Objectives: Canine visceral leishmaniasis (CVL) is one of the main neglected protozoan diseases in the world. Dogs play a fundamental role in the maintenance of Leishmania infantum in the Americas, and we have already encountered resistance ...
Kelvinson Fernandes Viana, Adrieli Barboza de Souza, Sara Torres, Maria Camila Escobar Garcia, Açucena Veleh Rivas, Alex Sander Rodrigues Cangussu, Francisca Hildemagna Guedes da Silva, Rodolfo Cordeiro Giunchetti   +7 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Source imaging method based on diagonal covariance bases and its applications to OPM-MEG

NeuroImage
Magnetoencephalography (MEG) is a noninvasive imaging technique used in neuroscience and clinical research. The source estimation of MEG involves solving a highly underdetermined inverse problem, which requires additional constraints to restrict the ...
Wen Li, Fuzhi Cao, Nan An, Wenli Wang, Chunhui Wang, Weinan Xu, Dexin Yu, Min Xiang, Xiaolin Ning   +8 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Structural convergence and membrane interactions of Aβ1-42 along the primary nucleation process studied by solid state NMR

Communications Chemistry
Non-specific disruption of cellular membranes induced by amyloidogenic aggregation of β-amyloid (Aβ) peptides remains a viable cytotoxicity mechanism in Alzheimer’s disease (AD).
Maurine K. Kengwerere, June M. Kenyaga, Peng Xiao, Shubha S. Gunaga, Faith J. Scott, Xyomara Wutoh-Hughes, James Wang, Brian Lum, Yan Sun, Frederic Mentink-Vigier, Tuo Wang, Wei Qiang   +11 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Artificial intelligence driven Mid-IR photoimaging device based on van der Waals heterojunctions of black phosphorus

Nanophotonics
Mid-infrared (Mid-IR) photodetection and imaging are pivotal across diverse applications, including remote sensing, communication, and spectral analysis.
Wang Ziqian, Wang Huide, Wang Chen, Bao Yushuo, Zheng Weiying, Weng Xiaoliang, Zhu Yihan, Liu Yi, Zhang Yule, Tian Xilin, Sun Shuo, Cao Rui, Shi Zhe, Chen Xing, Qiu Meng, Wang Hao, Liu Jun, Chen Shuqing, Zeng Yu-Jia, Liao Wugang, Huang Zhangcheng, Li Haiou, Gao Lingfeng, Li Jianqing, Fan Dianyuan, Zhang Han   +25 more
doaj   +1 more source

Optimizing DC-DC Converters through Interleaved Parallel Magnetic Integration: A Research Review

International Journal of Electrical, Energy and Power System Engineering
One of the main areas of focus for power electronics development nowadays is interleaved parallel magnetic integration technology. On the basis of introducing the staggered parallel connection technology of internal combustion engines and power systems ...
Muhammad Qasim Nawaz, Aimal Khan Khan
doaj   +1 more source

Numerical study on the effect of the magnetic field generated by circular coils with rectangular sections on plasma characteristics in low-pressure capacitive RF argon discharges [PDF]

AIP Advances
Based on electromagnetic theory, a model of the magnetic field generated by three circular coils with a rectangular cross-section was developed. The magnetic vector potential is computed using three-dimensional composite Simpson integration, and the ...
Yonghao Xu, Haoyu Gao, Feng Shi
doaj   +1 more source