Results 181 to 190 of about 2,516,794 (265)

Polydatin Alleviates APAP‐Induced Hepatotoxicity by Targeting C/EBPβ to Suppress the NLRP3 Inflammasome Signaling Pathway

open access: yesiNew Medicine, EarlyView.
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang   +6 more
wiley   +1 more source

Childhood adversity and psychotic‐like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development

open access: yesJCPP Advances, EarlyView.
Abstract Background Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods In youth from the Adolescent Brain Cognitive Development study (N = 3462), we investigated the effect of adversity at age 9 ...
Megan Thomas   +3 more
wiley   +1 more source

Tectonics of earthquake swarms in the Tokara Gap of northern Ryukyu Arc based on marine geological and geophysical surveys. [PDF]

open access: yesSci Rep
Koge H   +24 more
europepmc   +1 more source

White light reduces flight height of birds in low‐density migration corridor

open access: yesThe Journal of Wildlife Management, EarlyView.
We conducted an experiment to better understand the effects of artificial light at night treatments of varying spectral power distributions on in‐flight migratory bird behavior as measured by a portable radar. Broad‐spectrum white light emissions reduced avian flight height as compared to dark periods and more than other light treatments.
Miguel F. Jimenez   +6 more
wiley   +1 more source

KAT2A Promotes the Progression of Renal Cell Carcinoma by Regulating the Succinylation of SERPINE2

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) and angiogenesis are critical drivers of renal cell carcinoma (RCC) progression, yet their upstream regulatory mechanisms remain incompletely understood. This study aimed to investigate the role of KAT2A in RCC and elucidate the underlying molecular mechanism by which it promotes tumor progression.
Chang‐Cheng Liu, Xue‐Dong Li
wiley   +1 more source

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