Results 81 to 90 of about 2,719,193 (288)

Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging

Scientific Reports, 2022
Gene vectors to treat cystic fibrosis lung disease should be targeted to the conducting airways, as peripheral lung transduction does not offer therapeutic benefit. Viral transduction efficiency is directly related to the vector residence time.
Martin Donnelley, Patricia Cmielewski, Kaye Morgan, Juliette Delhove, Nicole Reyne, Alexandra McCarron, Nathan Rout-Pitt, Victoria Drysdale, Chantelle Carpentieri, Kathryn Spiers, Akihisa Takeuchi, Kentaro Uesugi, Naoto Yagi, David Parsons   +13 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Hybrid torque and SQUID magnetometry of individual magnetic nanotubes [PDF]

, 2015
For the experiments presented in this thesis, a hybrid magnetometer consisting of a ultra sensitive Si cantilever and a nano-scale superconducting quantum interference device (nanoSQUID) sensitive enough to measure a single nanoscale magnetic particle ...
Buchter, Arne
core   +1 more source

Aggregate structures of magnetic Janus particle suspensions via three-dimensional Monte Carlo simulations

Nihon Kikai Gakkai ronbunshu
In the present study, we investigated the transition in aggregate structures of a suspension composed of magnetic Janus particles under a uniform magnetic field.
Takeru YAMANOUCHI, Kazuya OKADA
doaj   +1 more source

Recent advances in magnetic targeting based on high magnetic field and magnetic particles

High Voltage, 2017
In the past few decades, the multifunctional magnetic drug carrier based on the magnetic nanoparticles and high magnetic field has been intensively researched. The magnetic drug carrier can be targeted to the tumour area not only by the chemical protocol
Zili Zhang, Ping He, Jinyan Zhang, Yikui Li, Qiuliang Wang   +4 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

High-temperature magnetic stability of small magnetite particles [PDF]

, 2003
The stability of magnetic domain structures of small grains of magnetite were examined between room temperature and the Curie temperature using a high-resolution three-dimensional micromagnetic algorithm.
Williams, W., Muxworthy, A.R., Dunlop, D.J., Williams, W.; id_orcid, Dunlop, D. J., Muxworthy, A. R.   +5 more
core   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

High-throughput, sheathless, magnetophoretic separation of magnetic and non-magnetic particles with a groove-based channel [PDF]

, 2016
The separation of target objects conjugated with magnetic particles is a significant application in biomedicine and clinical diagnosis. Conventional magnetophoresis-based devices use a sheath flow to pre-focus the particles into a single stream and ...
Yan, S, W. H. Li, Zhao, Q, J. Zhang, J. Ma, Q. Zhao, S. Yan, Ma, J, D. Yuan, Yuan, D, Li, WH, Zhang, J   +11 more
core   +1 more source